KPNA1 Antikörper (AA 1-300)
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- Target Alle KPNA1 Antikörper anzeigen
- KPNA1 (Karyopherin alpha 1 (Importin alpha 5) (KPNA1))
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Bindungsspezifität
- AA 1-300
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KPNA1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- MTTPGKENFR LKSYKNKSLN PDEMRRRREE EGLQLRKQKR EEQLFKRRNV ATAEEETEEE VMSDGGFHEA QISNMEMAPG GVITSDMIEM IFSKSPEQQL SATQKFRKLL SKEPNPPIDE VISTPGVVAR FVEFLKRKEN CTLQFESAWV LTNIASGNSL QTRIVIQAGA VPIFIELLSS EFEDVQEQAV WALGNIAGDS TMCRDYVLDC NILPPLLQLF SKQNRLTMTR NAVWALSNLC RGKSPPPEFA KVSPCLNVLS WLLFVSDTDV LADACWALSY LSDGPNDKIQ AVIDAGVCRR
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human KPNA1 (NP_002255.3).
- Isotyp
- IgG
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid freeze / thaw cycles
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-κB." in: Journal of virology, Vol. 91, Issue 8, (2017) (PubMed).
: "
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Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-κB." in: Journal of virology, Vol. 91, Issue 8, (2017) (PubMed).
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- Target
- KPNA1 (Karyopherin alpha 1 (Importin alpha 5) (KPNA1))
- Andere Bezeichnung
- KPNA1 (KPNA1 Produkte)
- Synonyme
- IPOA5 antikoerper, NPI-1 antikoerper, RCH2 antikoerper, SRP1 antikoerper, AW494490 antikoerper, NPI1 antikoerper, Rch2 antikoerper, mSRP1 antikoerper, si:ch211-161h7.7 antikoerper, karyopherin subunit alpha 1 antikoerper, importin alpha-1 subunit antikoerper, karyopherin (importin) alpha 1 antikoerper, karyopherin alpha 1 (importin alpha 5) antikoerper, KPNA1 antikoerper, Kpna1 antikoerper, EHI_124900 antikoerper, kpna1 antikoerper
- Hintergrund
- The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants.,KPNA1,IPOA5,NPI-1,RCH2,SRP1,Signal Transduction,Immunology & Inflammation,KPNA1
- Molekulargewicht
- 60 kDa
- Gen-ID
- 3836
- UniProt
- P52294
- Pathways
- M Phase, Protein targeting to Nucleus
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