FKBP1A Antikörper (AA 1-108)

Produktnummer ABIN3022504

Produktdetails anti-FKBP1A Antikörper

Target: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Bindungsspezifität: AA 1-108

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FKBP1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MGVQVETISP GDGRTFPKRG QTCVVHYTGM LEDGKKFDSS RDRNKPFKFM LGKQEVIRGW EEGVAQMSVG QRAKLTISPD YAYGATGHPG IIPPHATLVF DVELLKLE

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-108 of human FKBP12 (NP_463460.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FKBP1A

Target: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Andere Bezeichnung: FKBP1A (FKBP1A Produkte)

Synonyme: 12kDa antikoerper, FKBP12 antikoerper, FKBP12-T1 antikoerper, FKBP12-T2 antikoerper, Fkbp antikoerper, Fkbp1 antikoerper, mFKBP1 antikoerper, mFKBP12 antikoerper, FKBP-12 antikoerper, FKBP-1A antikoerper, FKBP1 antikoerper, Rotamase antikoerper, Fkbp12 antikoerper, ARABIDOPSIS THALIANA FK506-BINDING PROTEIN 12 antikoerper, ATFKBP12 antikoerper, FK506-binding protein 12 antikoerper, IMMUNOPHILIN antikoerper, MSJ1.19 antikoerper, MSJ1_19 antikoerper, PKC12 antikoerper, PKCI2 antikoerper, PPIASE antikoerper, FKBP1B antikoerper, Fkbp2 antikoerper, fj02g10 antikoerper, zgc:73373 antikoerper, wu:fj02g10 antikoerper, FKBP1A antikoerper, Bmfkbp13 antikoerper, zgc:103752 antikoerper, FK506 binding protein 1a antikoerper, FK506 binding protein 1A antikoerper, FK506-binding protein antikoerper, FK506-binding protein 12 antikoerper, FK506 binding protein 1Aa antikoerper, FK506 binding protein 1C antikoerper, FK506-binding protein 59 antikoerper, FK506 binding protein like antikoerper, FK506 binding protein 1A L homeolog antikoerper, FK506 binding protein 1Ab antikoerper, Fkbp1a antikoerper, FKBP1A antikoerper, Fkbp12 antikoerper, FKBP12 antikoerper, fkbp1aa antikoerper, FKBP1C antikoerper, EHI_180160 antikoerper, LOC5573443 antikoerper, Fkbp13 antikoerper, FKBPL antikoerper, fkbp1a.L antikoerper, fkbp1ab antikoerper

Hintergrund: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed.,FKBP1A,FKBP-12,FKBP-1A,FKBP1,FKBP12,PKC12,PKCI2,PPIASE,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,other,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Immunology & Inflammation,Regulator of mTOR complex function,Regulator,FKBP1A

Molekulargewicht: 11 kDa

Gen-ID: 2280

UniProt: P62942

Pathways: Negative Regulation of Transporter Activity, Methionine Biosynthetic Process