Dynactin 1 Antikörper (AA 945-1139)
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- Target Alle Dynactin 1 (DCTN1) Antikörper anzeigen
- Dynactin 1 (DCTN1)
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Bindungsspezifität
- AA 945-1139
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Dynactin 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP)
- Sequenz
- PGLVKDSPLL LQQISAMRLH ISQLQHENSI LKGAQMKASL ASLPPLHVAK LSHEGPGSEL PAGALYRKTS QLLETLNQLS THTHVVDITR TSPAAKSPSA QLMEQVAQLK SLSDTVEKLK DEVLKETVSQ RPGATVPTDF ATFPSSAFLR AKEEQQDDTV YMGKVTFSCA AGFGQRHRLV LTQEQLHQLH SRLIS
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 945-1139 of human DCTN1 (NP_001128513.1).
- Isotyp
- IgG
- Top Product
- Discover our top product DCTN1 Primärantikörper
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anti-Dynactin 1 (DCTN1) (C-Term) antibody
Verified DCTN1 Reaktivität: Human WB, ELISA, IHC, IF, FACS Wirt: Ziege Polyclonal unconjugated
anti-Dynactin 1 (DCTN1) (C-Term) antibodyDCTN1 Reaktivität: Human WB, IF, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Dynactin 1 (DCTN1) (AA 3-202) antibodyDCTN1 Reaktivität: Human, Maus, Ratte, Hund, Huhn WB, IF, IP, IHC (zinc) Wirt: Maus Monoclonal 1-p150Glued unconjugated
anti-Dynactin 1 (DCTN1) (AA 1084-1278) antibodyDCTN1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Dynactin 1 (DCTN1) (C-Term) antibodyDCTN1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Dynactin 1 (DCTN1) (N-Term) antibodyDCTN1 Reaktivität: Human WB, IP Wirt: Maus Monoclonal unconjugated
anti-Dynactin 1 (DCTN1) (AA 3-202) antibodyDCTN1 Reaktivität: Human, Maus, Ratte, Hund WB, IF, BI Wirt: Maus Monoclonal 12-P150GLUED unconjugated
anti-Dynactin 1 (DCTN1) antibodyDCTN1 Reaktivität: Human, Maus, Ratte IF Wirt: Kaninchen Polyclonal unconjugated
anti-Dynactin 1 (DCTN1) (AA 1-198) antibodyDCTN1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2E4-1C2 unconjugated
anti-Dynactin 1 (DCTN1) (AA 1216-1278) antibodyDCTN1 Reaktivität: Human WB, IHC, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB,1:500 - 1:2000,IP,1:50 - 1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid freeze / thaw cycles
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Dynactin 1 (DCTN1)
- Andere Bezeichnung
- DCTN1 (DCTN1 Produkte)
- Hintergrund
- This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA).,DCTN1,DAP-150,DP-150,P135,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cytoskeleton,Motor Proteins,Neuroscience,Neurodegenerative Diseases,DCTN1
- Molekulargewicht
- 126 kDa/127 kDa/136 kDa/138 kDa/140 kDa/141 kDa
- Gen-ID
- 1639
- UniProt
- Q14203
- Pathways
- M Phase, ER-Nucleus Signaling
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