Caspase 6 Antikörper (AA 24-293)

Produktnummer ABIN3022545

Produktdetails anti-Caspase 6 Antikörper

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Bindungsspezifität: AA 24-293

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: AFYKREMFDP AEKYKMDHRR RGIALIFNHE RFFWHLTLPE RRGTCADRDN LTRRFSDLGF EVKCFNDLKA EELLLKIHEV STVSHADADC FVCVFLSHGE GNHIYAYDAK IEIQTLTGLF KGDKCHSLVG KPKIFIIQAC RGNQHDVPVI PLDVVDNQTE KLDTNITEVD AASVYTLPAG ADFLMCYSVA EGYYSHRETV NGSWYIQDLC EMLGKYGSSL EFTELLTLVN RKVSQRRVDF CKDPSAIGKK QVPCFASMLT KKLHFFPKSN

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-293 of human Caspase-6 (NP_001217.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Caspase 6

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Andere Bezeichnung: CASP6 (CASP6 Produkte)

Hintergrund: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.,CASP6,MCH2,caspase-6,Caspase-6 p18,Caspase-6,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Caspases,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CASP6

Molekulargewicht: 22 kDa/33 kDa

Gen-ID: 839

UniProt: P55212

Pathways: Apoptose, Caspase Kaskade in der Apoptose