Phospholipase C beta 1 Antikörper (AA 917-1216)

Produktnummer ABIN3022699

Produktdetails anti-Phospholipase C beta 1 Antikörper

Target: Phospholipase C beta 1 (PLCB1) (phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1))

Bindungsspezifität: AA 917-1216

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Phospholipase C beta 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: KSFVKLQKKH YKEMKDLVKR HHKKTTDLIK EHTTKYNEIQ NDYLRRRAAL EKSAKKDSKK KSEPSSPDHG SSTIEQDLAA LDAEMTQKLI DLKDKQQQQL LNLRQEQYYS EKYQKREHIK LLIQKLTDVA EECQNNQLKK LKEICEKEKK ELKKKMDKKR QEKITEAKSK DKSQMEEEKT EMIRSYIQEV VQYIKRLEEA QSKRQEKLVE KHKEIRQQIL DEKPKLQVEL EQEYQDKFKR LPLEILEFVQ EAMKGKISED SNHGSAPLSL SSDPGKVNHK TPSSEELGGD IPGKEFDTPL

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 917-1216 of human PLCB1 (NP_056007.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Phospholipase C beta 1

Target: Phospholipase C beta 1 (PLCB1) (phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1))

Andere Bezeichnung: PLCB1 (PLCB1 Produkte)

Hintergrund: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.,PLCB1,EIEE12,PI-PLC,PLC-154,PLC-I,PLC-beta-1,PLC154,PLCB1A,PLCB1B,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Endocrine & Metabolism,Lipid Metabolism,AMPK Signaling Pathway,Neuroscience,Neurodegenerative Diseases,PLCB1

Molekulargewicht: 133 kDa/138 kDa

Gen-ID: 23236

UniProt: Q9NQ66

Pathways: WNT Signalweg, AMPK Signaling, Thyroid Hormone Synthesis, Inositol Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, G-protein mediated Events