CDKN1C Antikörper (AA 1-100)

Produktnummer ABIN3022819

Produktdetails anti-CDKN1C Antikörper

Target: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Bindungsspezifität: AA 1-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDKN1C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MSDASLRSTS TMERLVARGT FPVLVRTSAC RSLFGPVDHE ELSRELQARL AELNAEDQNR WDYDFQQDMP LRGPGRLQWT EVDSDSVPAF YRETVQVGRC

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CDKN1C/p57 Kip2 (NP_000067.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CDKN1C

Target: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Andere Bezeichnung: CDKN1C (CDKN1C Produkte)

Synonyme: BWCR antikoerper, BWS antikoerper, KIP2 antikoerper, WBS antikoerper, p57 antikoerper, p57Kip2 antikoerper, cb961 antikoerper, p27Xic1-a antikoerper, zgc:86618 antikoerper, AL024410 antikoerper, CDKI antikoerper, Kip2 antikoerper, p57(kip2) antikoerper, p57KIP2 antikoerper, cyclin dependent kinase inhibitor 1C antikoerper, cyclin-dependent kinase inhibitor 1Ca antikoerper, cyclin-dependent kinase inhibitor 1C (P57) antikoerper, cyclin-dependent kinase inhibitor 1C antikoerper, CDKN1C antikoerper, cdkn1ca antikoerper, Cdkn1c antikoerper

Hintergrund: This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.,CDKN1C,BWCR,BWS,KIP2,WBS,p57,p57Kip2,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,CDKN1C

Molekulargewicht: 31 kDa/32 kDa

Gen-ID: 1028

UniProt: P49918

Pathways: Zellzyklus, Dopaminergic Neurogenesis