NR1H3 Antikörper (AA 50-330)
-
- Target Alle NR1H3 Antikörper anzeigen
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
-
Bindungsspezifität
- AA 50-330
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser NR1H3 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- AGGTAGVGLE AAEPTALLTR AEPPSEPTEI RPQKRKKGPA PKMLGNELCS VCGDKASGFH YNVLSCEGCK GFFRRSVIKG AHYICHSGGH CPMDTYMRRK CQECRLRKCR QAGMREECVL SEEQIRLKKL KRQEEEQAHA TSLPPRASSP PQILPQLSPE QLGMIEKLVA AQQQCNRRSF SDRLRVTPWP MAPDPHSREA RQQRFAHFTE LAIVSVQEIV DFAKQLPGFL QLSREDQIAL LKTSAIEVML LETSRRYNPG SESITFLKDF SYNREDFAKA G
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 50-330 of human LXRalpha (NP_005684.2).
- Isotyp
- IgG
- Top Product
- Discover our top product NR1H3 Primärantikörper
-
-
- Applikationshinweise
- WB,1:500 - 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid freeze / thaw cycles
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
G004, a synthetic sulfonylurea compound, exerts anti-atherosclerosis effects by targeting SIRT1 in ApoE-/- mice." in: Vascular pharmacology, Vol. 89, pp. 49-57, (2017) (PubMed).
: "
-
G004, a synthetic sulfonylurea compound, exerts anti-atherosclerosis effects by targeting SIRT1 in ApoE-/- mice." in: Vascular pharmacology, Vol. 89, pp. 49-57, (2017) (PubMed).
-
- Target
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
- Andere Bezeichnung
- NR1H3 (NR1H3 Produkte)
- Synonyme
- NR1H3 antikoerper, LXR-a antikoerper, LXRA antikoerper, RLD-1 antikoerper, AU018371 antikoerper, LXR antikoerper, RLD1 antikoerper, Unr1 antikoerper, LXRalpha antikoerper, LXR-alpha antikoerper, im:7141239 antikoerper, wu:fd59b01 antikoerper, zgc:113339 antikoerper, zgc:158542 antikoerper, nuclear receptor subfamily 1 group H member 3 antikoerper, nuclear receptor subfamily 1, group H, member 3 antikoerper, NR1H3 antikoerper, nr1h3 antikoerper, Nr1h3 antikoerper
- Hintergrund
- The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,NR1H3,LXR-a,LXRA,RLD-1,LXR alpha,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Lipids,NR1H3
- Molekulargewicht
- 43 kDa/45 kDa/50 kDa
- Gen-ID
- 10062
- UniProt
- Q13133
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
-