MALT1 Antikörper (AA 125-450)

Produktnummer ABIN3023032

Produktdetails anti-MALT1 Antikörper

Target: MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))

Bindungsspezifität: AA 125-450

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MALT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: PGIKITVNPE SKAVLAGQFV KLCCRATGHP FVQYQWFKMN KEIPNGNTSE LIFNAVHVKD AGFYVCRVNN NFTFEFSQWS QLDVCDIPES FQRSVDGVSE SKLQICVEPT SQKLMPGSTL VLQCVAVGSP IPHYQWFKNE LPLTHETKKL YMVPYVDLEH QGTYWCHVYN DRDSQDSKKV EIIIDELNNL GHPDNKEQTT DQPLAKDKVA LLIGNMNYRE HPKLKAPLVD VYELTNLLRQ LDFKVVSLLD LTEYEMRNAV DEFLLLLDKG VYGLLYYAGH GYENFGNSFM VPVDAPNPYR SENCLCVQNI LKLMQEKETG LNVFLL

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 125-450 of human MALT1 (NP_776216.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-MALT1 Antikörper (ABIN3023032)

Yang, Liu, Liu, Liu, Zhang, Wang, Jiang, Wang: "miR-181d/MALT1 regulatory axis attenuates mesenchymal phenotype through NF-κB pathways in glioblastoma." in: Cancer letters, Vol. 396, pp. 1-9, (2017) (PubMed).

Details zu MALT1

Target: MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))

Andere Bezeichnung: MALT1 (MALT1 Produkte)

Synonyme: malt1 antikoerper, MALT1 antikoerper, mlt antikoerper, mlt1 antikoerper, MLT antikoerper, MLT1 antikoerper, A630046N12 antikoerper, D430033E09Rik antikoerper, MALT paracaspase 2 antikoerper, MALT1 paracaspase antikoerper, MALT1 paracaspase S homeolog antikoerper, paracaspase 3 antikoerper, malt2 antikoerper, MALT1 antikoerper, malt1.S antikoerper, Malt1 antikoerper, PCASP3 antikoerper

Hintergrund: This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.,MALT1,IMD12,MLT,MLT1,PCASP1,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Caspases,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,MALT1

Molekulargewicht: 91 kDa/92 kDa

Gen-ID: 10892

UniProt: Q9UDY8

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteine