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IRF3 Antikörper

IRF3 Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3023115
  • Target Alle IRF3 Antikörper anzeigen
    IRF3 (Interferon Regulatory Factor 3 (IRF3))
    Reaktivität
    • 147
    • 87
    • 54
    • 31
    • 18
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 146
    • 20
    • 2
    Kaninchen
    Klonalität
    • 133
    • 35
    Polyklonal
    Konjugat
    • 92
    • 11
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser IRF3 Antikörper ist unkonjugiert
    Applikation
    • 123
    • 69
    • 36
    • 32
    • 29
    • 27
    • 19
    • 11
    • 11
    • 10
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    A synthetic peptide of human IRF3
    Isotyp
    IgG
    Top Product
    Discover our top product IRF3 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid freeze / thaw cycles
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Qian, Fan, Liu, Wu, Zhang, Cui, Zhou, Hu, Wei, Chen, Li, Qian: "Seneca Valley Virus Suppresses Host Type I Interferon Production by Targeting Adaptor Proteins MAVS, TRIF, and TANK for Cleavage." in: Journal of virology, Vol. 91, Issue 16, (2017) (PubMed).

    Zhong, Wang, Fang, Zhang, Luo, Shang, Ouyang, Ouyang, Chen, Xiao: "Ubiquitin-specific proteases 25 negatively regulates virus-induced type I interferon signaling." in: PLoS ONE, Vol. 8, Issue 11, pp. e80976, (2013) (PubMed).

  • Target
    IRF3 (Interferon Regulatory Factor 3 (IRF3))
    Andere Bezeichnung
    IRF3 (IRF3 Produkte)
    Synonyme
    irf3 antikoerper, IRF3 antikoerper, C920001K05Rik antikoerper, IRF-3 antikoerper, interferon regulatory factor 3 antikoerper, interferon regulatory factor 7 antikoerper, irf3 antikoerper, IRF3 antikoerper, irf-3 antikoerper, Irf3 antikoerper, IRF7 antikoerper
    Hintergrund
    This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,IIAE7,IRF3,Epigenetics & Nuclear Signaling,Transcription Factors,Immunology & Inflammation,Cytokines,Interferons,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,IRF3
    Molekulargewicht
    12 kDa/16 kDa/33 kDa/47 kDa/49 kDa
    Gen-ID
    3661
    UniProt
    Q14653
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
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