This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants.,KLF5,BTEB2,CKLF,IKLF,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Apoptosis,Stem Cells,Mesenchymal Stem Cells,Cardiovascular,Angiogenesis,Heart,Hypertrophy,KLF5