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Histone H2A Antikörper (pSer139)

Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3023622
  • Target Alle Histone H2A Antikörper anzeigen
    Histone H2A
    Bindungsspezifität
    • 16
    • 11
    • 11
    • 8
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer139
    Reaktivität
    • 69
    • 49
    • 48
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 69
    • 2
    Kaninchen
    Klonalität
    • 58
    • 13
    Polyklonal
    Konjugat
    • 42
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Histone H2A Antikörper ist unkonjugiert
    Applikation
    • 49
    • 20
    • 17
    • 15
    • 14
    • 14
    • 11
    • 6
    • 6
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    TQASQ
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Phosphorylated Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    A synthetic phosphorylated peptide around S139 of human Histone H2AX (NP_002096.1).
    Isotyp
    IgG
    Top Product
    Discover our top product Histone H2A Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1mg/ml
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid freeze / thaw cycles
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Xiang, Laurent, Hsu, Nachtergaele, Lu, Sheng, Xu, Chen, Ouyang, Wang, Ling, Hsu, Zou, Jambhekar, He, Shi: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).

  • Target
    Histone H2A
    Abstract
    Histone H2A Produkte
    Hintergrund
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.,H2A.X,H2A/X,H2AX,Histone H2AX,H2AFX,histone H2AX,gamma H2A.X,γH2AX,Epigenetics & Nuclear Signaling,Histones,DNA Damage & Repair,Epigenetics & Nuclear Signaling,Epigenetic Modifications,Phosphorylation,Histone H2A
    Molekulargewicht
    15 kDa
    Gen-ID
    3014
    UniProt
    P16104
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