FOXM1 Antikörper (AA 1-350)

Produktnummer ABIN3023679

Produktdetails anti-FOXM1 Antikörper

Target: FOXM1 (Forkhead Box M1 (FOXM1))

Bindungsspezifität: AA 1-350

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Sequenz: MKTSPRRPLI LKRRRLPLPV QNAPSETSEE EPKRSPAQQE SNQAEASKEV AESNSCKFPA GIKIINHPTM PNTQVVAIPN NANIHSIITA LTAKGKESGS SGPNKFILIS CGGAPTQPPG LRPQTQTSYD AKRTEVTLET LGPKPAARDV NLPRPPGALC EQKRETCADG EAAGCTINNS LSNIQWLRKM SSDGLGSRSI KQEMEEKENC HLEQRQVKVE EPSRPSASWQ NSVSERPPYS YMAMIQFAIN STERKRMTLK DIYTWIEDHF PYFKHIAKPG WKNSIRHNLS LHDMFVRETS ANGKVSFWTI HPSANRYLTL DQVFKQQKRP NPELRRNMTI KTELPLGARR

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human FOXM1 (NP_973732.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,ChIP,1:20 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-FOXM1 Antikörper (ABIN3023679)

Li, Sun, Li, Lv, Semukunzi, Li, Yu, Yuan, Lin: "DT-13 synergistically enhanced vinorelbine-mediated mitotic arrest through inhibition of FOXM1-BICD2 axis in non-small-cell lung cancer cells." in: Cell death & disease, Vol. 8, Issue 5, pp. e2810, (2018) (PubMed).

Jiang, Liao, He, Xin, Tu, Kong, Cui, Wang, Quan, Li, Zhang, Wang: "FoxM1 Directs STAT3 Expression Essential for Human Endometrial Stromal Decidualization." in: Scientific reports, Vol. 5, pp. 13735, (2016) (PubMed).

Details zu FOXM1

Target: FOXM1 (Forkhead Box M1 (FOXM1))

Andere Bezeichnung: FOXM1 (FOXM1 Produkte)

Synonyme: FKHL16 antikoerper, FOXM1B antikoerper, HFH-11 antikoerper, HFH11 antikoerper, HNF-3 antikoerper, INS-1 antikoerper, MPHOSPH2 antikoerper, MPP-2 antikoerper, MPP2 antikoerper, PIG29 antikoerper, TGT3 antikoerper, TRIDENT antikoerper, FOXM1 antikoerper, AA408308 antikoerper, AW554517 antikoerper, BB238854 antikoerper, Fkh16 antikoerper, Foxm1b antikoerper, HFH-11B antikoerper, Mpm2 antikoerper, WIN antikoerper, Trident antikoerper, fkhl16 antikoerper, foxm1l antikoerper, hfh-11 antikoerper, mpp2 antikoerper, zgc:63854 antikoerper, forkhead box M1 antikoerper, forkhead box M1 S homeolog antikoerper, FOXM1 antikoerper, Foxm1 antikoerper, foxm1 antikoerper, foxm1.S antikoerper

Hintergrund: The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene.,FKHL16,FOXM1B,HFH-11,HFH11,HNF-3,INS-1,MPHOSPH2,MPP-2,MPP2,PIG29,TRIDENT,FOXM1,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,FOXM1

Molekulargewicht: 82 kDa/84 kDa/88 kDa

Gen-ID: 2305

UniProt: Q08050

Pathways: Positive Regulation of Response to DNA Damage Stimulus