PDE8B Antikörper (Internal Region)
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- Target Alle PDE8B Antikörper anzeigen
- PDE8B (phosphodiesterase 8B (PDE8B))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PDE8B Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- This antibody detects Phosphodiesterase 8B (PDE8B) at internal domain.
- Aufreinigung
- Immunoaffinity chromatography
- Immunogen
- PDE8B antibody was raised against synthetic peptide from internal domain of human PDE8B.
- Top Product
- Discover our top product PDE8B Primärantikörper
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- Applikationshinweise
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Immunohistochemistry on paraffin sections (5 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0,3 mg/mL
- Buffer
- PBS containing 0.09 % sodium azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
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- Target
- PDE8B (phosphodiesterase 8B (PDE8B))
- Andere Bezeichnung
- PDE8B (PDE8B Produkte)
- Synonyme
- PDE8B antikoerper, ADSD antikoerper, PPNAD3 antikoerper, B230331L10Rik antikoerper, C030047E14Rik antikoerper, RNPDE8B antikoerper, phosphodiesterase 8B antikoerper, high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B antikoerper, PDE8B antikoerper, LOC100468338 antikoerper, pde8b antikoerper, Pde8b antikoerper
- Hintergrund
- Phosphodiesterase 8B, is a high affinity, cAMP-specific phosphodiesterase. Enhanced PDE8B activity has been associated with the phenotypic expression of Gsalpha mutations in human pituitary tumors. PDE8B is absent in normal pituitary but present in GH-secreting adenomas. PDE8B activity is inhibited by dipyridamole, but it is insensitive to rolipram, zaprinast, or IBMX.Synonyms: 5'-cyclic phosphodiesterase 8B, ADSD, Cell proliferation-inducing gene 22 protein, High affinity cAMP-specific and IBMX-insensitive 3', PIG22, PPNAD3, Phosphodiesterase 8B, hsPDE8B
- Gen-ID
- 8622
- NCBI Accession
- NP_001025022
- UniProt
- O95263
- Pathways
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process
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