CHRM1 Antikörper (AA 303-317)

Produktnummer ABIN3029680

Produktdetails anti-CHRM1 Antikörper

Target: CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))

Bindungsspezifität: AA 303-317

Reaktivität: Ratte, Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Amino acids 303-317 (KMPMVDPEAQAPTKQ-human) were used as the immunogen for this muscarinic AChR antibody (100% mouse homology).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the AChR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the AChR antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu CHRM1

Target: CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))

Andere Bezeichnung: AChR (Muscarinic) (CHRM1 Produkte)

Synonyme: M1 antikoerper, CHRM1 antikoerper, HM1 antikoerper, M1R antikoerper, mAChR antikoerper, Chrm-1 antikoerper, cholinergic receptor muscarinic 1 antikoerper, cholinergic receptor, muscarinic 1 antikoerper, cholinergic receptor, muscarinic 1, CNS antikoerper, CHRM1 antikoerper, Chrm1 antikoerper

Hintergrund: Muscarinic acetylcholine receptor 1 is a muscarinic receptor. The muscarinic cholinergic receptors belong to a larger family of GPCRs. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. AChR is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract.

UniProt: P11229

Pathways: Synaptic Membrane