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EPH Receptor B3 Antikörper (C-Term)

EPHB3 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3029711
  • Target Alle EPH Receptor B3 (EPHB3) Antikörper anzeigen
    EPH Receptor B3 (EPHB3)
    Bindungsspezifität
    • 15
    • 9
    • 8
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 72
    • 27
    • 15
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 63
    • 10
    • 1
    Kaninchen
    Klonalität
    • 65
    • 9
    Polyklonal
    Konjugat
    • 39
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EPH Receptor B3 Antikörper ist unkonjugiert
    Applikation
    • 58
    • 30
    • 17
    • 14
    • 13
    • 13
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    Antigen affinity
    Immunogen
    An amino acid sequence from the C-terminus of human Eph receptor B3 (SIQDMRLQMNQTLPVQV) was used as the immunogen for this EphB3 antibody (100% homologous in human, mouse and rat).
    Isotyp
    IgG
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  • Applikationshinweise
    The stated application concentrations are suggested starting amounts. Titration of the EphB3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Lagerung
    -20 °C
    Informationen zur Lagerung
    After reconstitution, the EphB3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    EPH Receptor B3 (EPHB3)
    Andere Bezeichnung
    EphB3 Ephrin Receptor B3 (EPHB3 Produkte)
    Hintergrund
    Ephrin Receptor B3, is also known as human embryo kinase2 (HEK2) or Eph-like tyrosine kinase 2 (ETK2) is a member of the EPH/ELK family of tyrosine kinases. The gene encodes a 998-amino acid polypeptide having a single putative transmembrane domain, a secretory signal sequence, and two fibronectin repeats. The gene is mapped to human chromosome 3q21-qter. EphB3 interacts with two ligands of EPH-related kinases (LERKs), LERK2/EFNB1 and LERK5/EFNB2. Coincubation of EphB3- and LERK2-expressing cells induces cell-cell adhesion and aggregation. Additionally, coexpression of the two proteins results in reduced kinase activity of EphB3.
    UniProt
    P54753
    Pathways
    RTK Signalweg
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