CXCR5 Antikörper (C-Term)

Produktnummer ABIN3030517

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CXCR5 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für CXCR5 Antikörper (C-Term) (ABIN3030517)

Target: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCR5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CXCR5 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: CXCR5 Antibody / BLR1 / MDR15

Sequenz: SSLSESENAT SLTTF

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human Chemokine CXC Motif Receptor 5 (SSLSESENATSLTTF) was used as the immunogen for this CXCR5 antibody (100% homologous in human, mouse and rat).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the CXCR5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the CXCR5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu CXCR5

Target: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Andere Bezeichnung: CXCR5

Hintergrund: Chemokine CXC Motif Receptor 5, also known as BLR1 and MDR15, is a G protein-coupled seven transmembrane receptor for chemokine CXCL13 (also known as BLC) and belongs to the CXC chemokine receptor family. In humans, the protein is encoded by the CXCR5 gene. The gene plays an essential role in B cell migration. Reif et al.(2002) concluded that their findings defined the mechanism of B-cell relocalization in response to antigen, and established that cell position in vivo can be determined by the balance of responsiveness to chemoattractants made in separate but adjacent zones. Chan et al.(2003) investigated the expression of chemokines and chemokine receptors in eyes with primary intraocular B-cell lymphoma(PIOL).

UniProt: P32302