FAF1 Antikörper (N-Term)

Produktnummer ABIN3030906

Produktdetails anti-FAF1 Antikörper

Target: FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of human FAF1 (MASNMDREMILADFQACTGIEN) was used as the immunogen for this FAF1 antibody (100% homologous in human, mouse and rat).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the FAF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the FAF1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu FAF1

Target: FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))

Andere Bezeichnung: FAF1 (FAF1 Produkte)

Synonyme: faf1 antikoerper, MGC53741 antikoerper, MGC80303 antikoerper, FAF1 antikoerper, zgc:55752 antikoerper, wu:fc25h12 antikoerper, HFAF1s antikoerper, UBXD12 antikoerper, UBXN3A antikoerper, hFAF1 antikoerper, AA408698 antikoerper, Dffrx antikoerper, Fam antikoerper, Fas (TNFRSF6) associated factor 1 S homeolog antikoerper, Fas (TNFRSF6) associated factor 1 L homeolog antikoerper, Fas associated factor 1 antikoerper, Fas (TNFRSF6) associated factor 1 antikoerper, Fas-associated factor 1 antikoerper, faf1.S antikoerper, faf1.L antikoerper, FAF1 antikoerper, faf1 antikoerper, Faf1 antikoerper

Hintergrund: Fas-associated factor-1(FAF1) is a Fas-binding pro-apoptotic protein that is a component of the death-inducing signaling complex in Fas-mediated apoptosis. FAF1 is involved in negative regulation of NF-kappaB activation. In addition to the previously known function as a component of the Fas death-inducing signaling complex, i.e. NF-kappaB activity suppressor by cytoplasmic retention of NF-kappaB p65 via physical interaction. hFAF1 was expressed abundantly in testis, skeletal muscle, and heart as 2.8 kb mRNA. Polyclonal antibody against hFAF1 detected 74 kD protein, a deduced protein size from the ORF and 40 kD protein in some cell lines.

UniProt: Q9UNN5

Pathways: Maintenance of Protein Location