Glutaredoxin 2 Antikörper (Middle Region)

Produktnummer ABIN3031080

Produktdetails anti-Glutaredoxin 2 Antikörper

Target: Glutaredoxin 2 (GRX2)

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutaredoxin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the middle region of human GLRX2 (EYGNQFQDALYKMTGER) was used as the immunogen for this Glutaredoxin 2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Glutaredoxin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Glutaredoxin 2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Glutaredoxin 2

Target: Glutaredoxin 2 (GRX2)

Andere Bezeichnung: Glutaredoxin 2 (GRX2 Produkte)

Synonyme: ECK1049 antikoerper, JW1051 antikoerper, CGI-133 antikoerper, GRX2 antikoerper, 1700010P22Rik antikoerper, AI645710 antikoerper, Grx2 antikoerper, glutaredoxin 2 (Grx2) antikoerper, glutaredoxin Grx2 antikoerper, thioredoxin antikoerper, glutaredoxin 2 antikoerper, glutaredoxin 2 (thioltransferase) antikoerper, grxB antikoerper, grx2 antikoerper, AF_RS10790 antikoerper, GLRX2 antikoerper, Glrx2 antikoerper

Hintergrund: Glutaredoxin-2 also known as GLRX2 and GRX2, is a protein that in humans is encoded by the GLRX2 gene. Glutaredoxins are a family of glutathione-dependent hydrogen donors that participate in a variety of cellular redox reactions. By sequence analysis, Lundberg et al.(2001) and Gladyshev et al.(2001) identified the GLRX2 gene within a clone mapping to chromosome 1q31.2-q31.3. Lundberg et al.(2001) determined that the gene contains 5 exons spanning about 9.6 kb. The GLRX2B transcript uses a first exon(exon 1B) located upstream from the first exon used by the GLRX2A transcript(exon 1A), suggesting that alternative splicing generates the isoforms. Lundberg et al.(2001)assayed reductase activity in recombinant proteins of both GLRX2 isoforms. They found that both have GSH-dependent dehydroascorbate reductase activity and 2-hydroxyethyl disulfide reductase activity.

UniProt: Q9NS18

Pathways: Cell RedoxHomeostasis