HSPH1 Antikörper (AA 713-733)

Produktnummer ABIN3031140

Produktdetails anti-HSPH1 Antikörper

Target: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Bindungsspezifität: AA 713-733

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSPH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Aufreinigung: Antigen affinity

Immunogen: Amino acids 713-733 (EVMEWMNNVMNAQAKKSLDQD-human) were used as the immunogen for this HSP105 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the HSP105 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Hsp105 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu HSPH1

Target: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Andere Bezeichnung: HSP105 (HSPH1 Produkte)

Synonyme: hsp105 antikoerper, hsp105a antikoerper, hsp105b antikoerper, hsp110 antikoerper, hsph1b antikoerper, Hsp105 antikoerper, HSP105 antikoerper, HSP105A antikoerper, HSP105B antikoerper, NY-CO-25 antikoerper, 105kDa antikoerper, AI790491 antikoerper, Hsp110 antikoerper, hsp-E7I antikoerper, hsph1 antikoerper, hsph1a antikoerper, heat shock protein family H (Hsp110) member 1 antikoerper, heat shock protein family H (Hsp110) member 1 S homeolog antikoerper, heat shock protein 105 kDa antikoerper, heat shock 105kDa/110kDa protein 1 antikoerper, heat shock protein family H (Hsp110) member 1 L homeolog antikoerper, hsph1 antikoerper, hsph1.S antikoerper, HSPH1 antikoerper, LOC100546590 antikoerper, Hsph1 antikoerper, hsph1.L antikoerper

Hintergrund: Heat shock protein 105, also called HSPH1 or HSP110, is a protein that in humans is encoded by the HSPH1 gene. Immunohistochemical analysis localizes HSP105 mainly in the cytoplasm. Database analysis indicates that both HSP105 isoforms are highly conserved during evolution. By analysis of radiation hybrids and human/rodent hybrid cell lines, the HSPH1 gene is mapped to chromosome 13. Both HSP105alpha and HSP105beta are upregulated in HeLa cells exposed to heat shock. HSP105alpha, but not HSP105beta, is also upregulate in response to other cell stresses. Following heat shock, HSP105 relocalizes from a cytoplasmic to perinuclear position. Additionally, it may constitute a major determinant for both prognosis and treatment response in colorectal cancer.

UniProt: Q92598