HSD17B4 Antikörper (C-Term)

Produktnummer ABIN3031274

Produktdetails anti-HSD17B4 Antikörper

Target: HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD17B4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human HSD17B4 (NIMLSQKLQMILKDYAKL) was used as the immunogen for this 17-beta-Hydroxysteroid dehydrogenase 4 antibody (100% homologous in human, mouse and rat).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the 17-beta-Hydroxysteroid dehydrogenase 4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the 17-beta-Hydroxysteroid dehydrogenase 4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu HSD17B4

Target: HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))

Andere Bezeichnung: 17-beta-Hydroxysteroid Dehydrogenase 4 (HSD17B4) (HSD17B4 Produkte)

Synonyme: zgc:55545 antikoerper, zgc:77300 antikoerper, CG3415 antikoerper, DmMFE-2 antikoerper, Dmel\\CG3415 antikoerper, MFE-2 antikoerper, DBP antikoerper, MPF-2 antikoerper, PRLTS1 antikoerper, SDR8C1 antikoerper, 17-beta-HSD antikoerper, 17[b]-HSD antikoerper, 4 antikoerper, MFP2 antikoerper, Mfp-2 antikoerper, perMFE-2 antikoerper, hydroxysteroid (17-beta) dehydrogenase 4 antikoerper, hydroxysteroid 17-beta dehydrogenase 4 antikoerper, peroxisomal Multifunctional enzyme type 2 antikoerper, hsd17b4 antikoerper, HSD17B4 antikoerper, Mfe2 antikoerper, Hsd17b4 antikoerper

Hintergrund: The HSD17B4 gene encodes an enzyme involved in peroxisomal fatty acid beta-oxidation. It was first identified as a 17-beta-estradiol dehydrogenase. Peroxisomal beta-oxidation of fatty acids is catalyzed by 3 enzymes: acyl-CoA oxidase, the D-bifunctional enzyme with enoyl-CoA-hydratase and D-3-hydroxyacyl-CoA dehydrogenase activity, and 3-ketoacyl-CoA thiolase. The D- and L-bifunctional proteins have different substrate specificities. The D-bifunctional protein catalyzes the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids and also acts in shortening cholesterol for bile acid formation. In contrast, the L-specific bifunctional protein does not have the latter 2 activities.

UniProt: F5HE57

Pathways: Monocarboxylic Acid Catabolic Process