Kallikrein 10 Antikörper (C-Term)

Produktnummer ABIN3031526

Produktdetails anti-Kallikrein 10 Antikörper

Target: Kallikrein 10 (KLK10)

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kallikrein 10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human Kallikrein 10 (SAQHPAVYTQICKY) was used as the immunogen for this Kallikrein 10 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Kallikrein 10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Kallikrein 10 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Kallikrein 10

Target: Kallikrein 10 (KLK10)

Andere Bezeichnung: Kallikrein 10 (KLK10 Produkte)

Synonyme: KLK10 antikoerper, 2300002A13Rik antikoerper, NES1 antikoerper, PRSSL1 antikoerper, kallikrein related peptidase 10 antikoerper, kallikrein related-peptidase 10 antikoerper, kallikrein-related peptidase 10 antikoerper, KLK10 antikoerper, Klk10 antikoerper

Hintergrund: Kallikrein-related peptidase 10, also known as KLK10, PRSSL1 or NES1, belongs to the kallikrein subfamily of serine proteases, which are involved in a variety of enzymatic processes. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. KLK10 contains 12 conserved cysteines in its protease domain that are expected to form 6 disulfide bonds, as in other serine proteases. RT-PCR detected variable levels of KLK10 expression in nearly all of the 35 adult and fetal tissues examined. The gene contains 6 exons, the first of which is noncoding. By fluorescence in situ hybridization, Polikoff et al.(1997) mapped the gene to 19q13.3. By genomic sequence analysis,Gan et al.(2000) mapped the gene within the KLK gene cluster on chromosome 19q13. This cluster includes 13 KLK genes and 5 pseudogenes.

UniProt: O43240

Pathways: Komplementsystem