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MTDH Antikörper (AA 101-270)

MTDH Reaktivität: Human, Maus, Ratte WB, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3031760
  • Target Alle MTDH Antikörper anzeigen
    MTDH (Metadherin (MTDH))
    Bindungsspezifität
    • 16
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 101-270
    Reaktivität
    • 49
    • 17
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 40
    • 7
    • 3
    Kaninchen
    Klonalität
    • 45
    • 5
    Polyklonal
    Konjugat
    • 28
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MTDH Antikörper ist unkonjugiert
    Applikation
    • 40
    • 15
    • 13
    • 13
    • 11
    • 10
    • 8
    • 8
    • 7
    • 4
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Aufreinigung
    Antigen affinity
    Immunogen
    Human partial recombinant protein (AA 101-270) was used as the immunogen for this LYRIC antibody.
    Isotyp
    IgG
    Top Product
    Discover our top product MTDH Primärantikörper
  • Applikationshinweise
    The stated application concentrations are suggested starting amounts. Titration of the LYRIC antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,ICC: 0.5-1 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Lagerung
    -20 °C
    Informationen zur Lagerung
    After reconstitution, the LYRIC antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    MTDH (Metadherin (MTDH))
    Andere Bezeichnung
    LYRIC (Metadherin) (MTDH Produkte)
    Synonyme
    MGC75963 antikoerper, 2610103J23Rik antikoerper, 3D3 antikoerper, 3D3/Lyric antikoerper, AEG-1 antikoerper, AV353288 antikoerper, D8Bwg1112e antikoerper, Lyric antikoerper, AEG1 antikoerper, LYRIC antikoerper, LYRIC/3D3 antikoerper, metadherin antikoerper, mtdh antikoerper, MTDH antikoerper, Mtdh antikoerper
    Hintergrund
    MTDH (Metadherin), also known as LYRIC or astrocyte elevated gene-1 protein (AEG-1), is a protein that in humans is encoded by the MTDH gene. It is involved in < a href=../search_result.php?search_txt=hif-1 alpha>HIF-1 alpha mediated angiogenesis, interacts with SND1 and is involved in RNA-induced silencing complex (RISC), and plays a very important role in RISC and miRNA functions. LYRIC induces an oncogene called Late SV40 factor (LSF/TFCP2) which is involved in thymidylate synthase (TS) induction and DNA biosynthesis synthesis. Late SV40 factor enhances angiogenesis by transcriptionally up-regulating matrix metalloproteinase-9 (< a href=../search_result.php?search_txt=mmp9>MMP9). LYRIC acts as an oncogene in melanoma, malignant glioma, breast cancer and hepatocellular carcinoma. It is highly expressed in these cancers and helps in progression and development of these cancers. It is induced by c-Myc oncogene and plays very important role in anchorage independent growth of cancer cells.
    Gen-ID
    92140
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization
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