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Microtubule Star Antikörper (N-Term)

MTS Reaktivität: Human, Maus, Ratte IHC (p), WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3031776
  • Target Alle Microtubule Star (MTS) Produkte
    Microtubule Star (MTS)
    Bindungsspezifität
    N-Term
    Reaktivität
    Human, Maus, Ratte
    Wirt
    Kaninchen
    Klonalität
    Polyklonal
    Applikation
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Aufreinigung
    Antigen affinity
    Immunogen
    An amino acid sequence from the N-terminus of human PPP2CA (FTKELDQWIEQLNEC) was used as the immunogen for this PP2Ac antibody (100% homologous in human, mouse and rat).
    Isotyp
    IgG
  • Applikationshinweise
    Variations in secondary/substrate sensitivities and test protocols may require the PP2Ac antibody to be titrated for optimal performance.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Lagerung
    -20 °C
    Informationen zur Lagerung
    The lyophilized PP2Ac antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freeze/thaws.
  • Target
    Microtubule Star (MTS)
    Andere Bezeichnung
    PP2Ac
    Synonyme
    AI115466 antikoerper, D8Ertd766e antikoerper, PP2Ac antikoerper, PP2CA antikoerper, PP2Calpha antikoerper, RP-C antikoerper, protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform antikoerper, protein phosphatase 2 catalytic subunit alpha antikoerper, Ppp2cb antikoerper, PPP2CA antikoerper
    Hintergrund
    The catalytic subunit of human protein phosphatase 2A (PPP2CA) encodes a 309-amino acid polypeptide. It is predicted to be important for phosphatase enzymatic activity. Methylation of the C-terminal leucine residue (Leu309) of PPP2CA is known to regulate catalytic activity in vitro. Furthermore, PP2A has a fundamental role in cardiac function, and suggests that disturbances in protein phosphatase expression and activity may cause or exacerbate the course of cardiac diseases.
    UniProt
    P67775
    Pathways
    PI3K-Akt Signalweg, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades
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