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MPG Antikörper (C-Term)

MPG Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3031925
  • Target Alle MPG Antikörper anzeigen
    MPG (N-Methylpurine-DNA Glycosylase (MPG))
    Bindungsspezifität
    • 15
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 41
    • 8
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 39
    • 3
    • 1
    Kaninchen
    Klonalität
    • 40
    • 3
    Polyklonal
    Konjugat
    • 23
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MPG Antikörper ist unkonjugiert
    Applikation
    • 37
    • 13
    • 13
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB)
    Aufreinigung
    Antigen affinity
    Immunogen
    An amino acid sequence from the C-terminus of human MPG (NKSFDQRDLAQDEAVW) was used as the immunogen for this MPG antibody.
    Isotyp
    IgG
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  • Applikationshinweise
    The stated application concentrations are suggested starting amounts. Titration of the MPG antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Lagerung
    -20 °C
    Informationen zur Lagerung
    After reconstitution, the MPG antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    MPG (N-Methylpurine-DNA Glycosylase (MPG))
    Andere Bezeichnung
    MPG (MPG Produkte)
    Synonyme
    AAG antikoerper, ADPG antikoerper, APNG antikoerper, CRA36.1 antikoerper, MDG antikoerper, Mid1 antikoerper, PIG11 antikoerper, PIG16 antikoerper, anpg antikoerper, 9830006D05 antikoerper, AI326268 antikoerper, Aag antikoerper, zgc:162984 antikoerper, si:xx-187g17.9 antikoerper, MPG antikoerper, MPGR antikoerper, N-methylpurine DNA glycosylase antikoerper, N-methylpurine-DNA glycosylase antikoerper, si:xx-by187g17.9 antikoerper, MPG antikoerper, Mpg antikoerper, mpg antikoerper, si:xx-by187g17.9 antikoerper, CpB0526 antikoerper, gll2491 antikoerper
    Hintergrund
    N-Methylpurine-DNA glycosylase is encoded by the MPG gene, mapped to human chromosome 16 by analysis of a panel of DNAs from mouse/human and hamster/human hybrid cell lines. The gene was expressed in all cell lines and tissues examined, but was found at particularly high levels in a colon adenocarcinoma cell line (HT29). The completely characterized human gene was found to span 7 to 8 kb of genomic DNA and to be localized 75 kb upstream of the embryonic zeta-globin gene. To assess the contribution of MPG to the repair of several mutagenic lesions in vivo, Hang et al.(1997) biochemically analyzed cell-free extracts of tissues from mice with a targeted deletion of the gene. Following treatment with DNA-methylating agents, increased persistence of 7-methylguanine (meG) was found in liver sections of MPG knockout mice in comparison with wildtype mice, demonstrating an in vivo phenotype for the MPG-null animals.
    UniProt
    P29372
    Pathways
    DNA Reparatur
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