Neuregulin 1 Antikörper (C-Term)

Produktnummer ABIN3031973

Produktdetails anti-Neuregulin 1 Antikörper

Target: Neuregulin 1 (NRG1)

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neuregulin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human Neuregulin 1 (RFSTQEEIQARLSSVIANQD) was used as the immunogen for this NRG1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the NRG1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the NRG1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Neuregulin 1

Target: Neuregulin 1 (NRG1)

Andere Bezeichnung: NRG1 (NRG1 Produkte)

Synonyme: 6030402G23Rik antikoerper, ARIA antikoerper, D230005F13Rik antikoerper, GGF antikoerper, GGFII antikoerper, HRG antikoerper, HRGalpha antikoerper, Hgl antikoerper, NDF antikoerper, SMDF antikoerper, GGF2 antikoerper, HGL antikoerper, HRG1 antikoerper, HRGA antikoerper, MST131 antikoerper, NRG-1 antikoerper, heregulin antikoerper, nrg1-A antikoerper, pro-neuregulin-1 antikoerper, NRG1 antikoerper, wu:fm70e01 antikoerper, DKFZp459A1838 antikoerper, neuregulin 1 antikoerper, histidine rich glycoprotein antikoerper, neuregulin 1 L homeolog antikoerper, Nrg1 antikoerper, NRG1 antikoerper, HRG antikoerper, nrg1.L antikoerper, nrg1 antikoerper

Hintergrund: Neuregulin 1, also known as ARIA, NDF or HRGA, is a protein that in humans is encoded by the NRG1 gene. It is one of four proteins in the neuregulin family that act on the EGFR family of receptors. By in situ hybridization of a tritium-labeled probe to human metaphase spreads, Orr-Urtreger et al.(1993) localized the gene to 8p21-p12. In mouse embryos 14.5 days postcoitum, Orr-Urtreger et al.(1993) found that NRG1 expression is confined predominantly to the central and peripheral nervous systems, including the neuroepithelium that lines the lateral ventricles of the brain, the ventral horn of the spinal cord, and the intestinal as well as dorsal root ganglia.

UniProt: Q02297

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation