Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

PIAS1 Antikörper (AA 636-651)

PIAS1 Reaktivität: Human, Maus, Ratte WB, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3032369
  • Target Alle PIAS1 Antikörper anzeigen
    PIAS1 (Protein Inhibitor of Activated STAT, 1 (PIAS1))
    Bindungsspezifität
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 636-651
    Reaktivität
    • 42
    • 11
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 39
    • 4
    Kaninchen
    Klonalität
    • 40
    • 3
    Polyklonal
    Konjugat
    • 26
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PIAS1 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 20
    • 19
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Aufreinigung
    Antigen affinity
    Immunogen
    Amino acids 636-651 (DTASIFGIIPDIISLD-human) were used as the immunogen for this PIAS1 antibody (100% homologous in human, mouse and rat).
    Isotyp
    IgG
    Top Product
    Discover our top product PIAS1 Primärantikörper
  • Applikationshinweise
    The stated application concentrations are suggested starting amounts. Titration of the PIAS1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Lagerung
    -20 °C
    Informationen zur Lagerung
    After reconstitution, the PIAS1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    PIAS1 (Protein Inhibitor of Activated STAT, 1 (PIAS1))
    Andere Bezeichnung
    PIAS1 (PIAS1 Produkte)
    Synonyme
    2900068C24Rik antikoerper, Ddxbp1 antikoerper, GBP antikoerper, DDXBP1 antikoerper, GU/RH-II antikoerper, ZMIZ3 antikoerper, ddxbp1 antikoerper, gbp antikoerper, pias antikoerper, pias1-A antikoerper, xPAIS1 antikoerper, xPIAS1 antikoerper, zmiz3 antikoerper, protein inhibitor of activated STAT 1 antikoerper, protein inhibitor of activated STAT, 1 antikoerper, protein inhibitor of activated STAT, 1a antikoerper, protein inhibitor of activated STAT 1 L homeolog antikoerper, PIAS1 antikoerper, Pias1 antikoerper, pias1a antikoerper, pias1.L antikoerper
    Hintergrund
    E3 SUMO-protein ligase PIAS1 is an enzyme that in humans is encoded by the PIAS1 gene. This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1(signal transducer and activator of transcription-1)] family. It contains a putative zinc-binding motif and a highly acidic region. PIAS1 inhibited STAT1-mediated gene activation in response to interferon when expressed in mammalian cells. It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis. PIAS1 can also function as a SUMO ligase, or possibly as a tightly bound regulator of it, toward p53.
    UniProt
    O75925
    Pathways
    JAK-STAT Signalweg, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C
Sie sind hier:
Kundenservice