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SNRPN Antikörper (N-Term)

SNRPN Reaktivität: Human, Maus, Ratte WB, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3032638
  • Target Alle SNRPN Antikörper anzeigen
    SNRPN (Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN))
    Bindungsspezifität
    • 11
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 32
    • 13
    • 12
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 26
    • 6
    Kaninchen
    Klonalität
    • 28
    • 4
    Polyklonal
    Konjugat
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser SNRPN Antikörper ist unkonjugiert
    Applikation
    • 32
    • 19
    • 16
    • 6
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Aufreinigung
    Antigen affinity
    Immunogen
    An amino acid sequence from the N-terminus of human SNRPN (FKAFDKHMNLILCDCDEF) was used as the immunogen for this SNRPN antibody (100% homologous in human, mouse and rat).
    Isotyp
    IgG
    Top Product
    Discover our top product SNRPN Primärantikörper
  • Applikationshinweise
    The stated application concentrations are suggested starting amounts. Titration of the SNRPN antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Lagerung
    -20 °C
    Informationen zur Lagerung
    After reconstitution, the SNRPN antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    SNRPN (Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN))
    Andere Bezeichnung
    SNRPN (SNRPN Produkte)
    Synonyme
    SNRB' antikoerper, SNRPB' antikoerper, Snrpn antikoerper, zgc:77315 antikoerper, HCERN3 antikoerper, PWCR antikoerper, RT-LI antikoerper, SM-D antikoerper, SMN antikoerper, SNRNP-N antikoerper, SNURF-SNRPN antikoerper, sm-N antikoerper, 2410045I01Rik antikoerper, Peg4 antikoerper, Pwcr1 antikoerper, FE 294 antikoerper, FE 294 psi antikoerper, FE294 antikoerper, FE294 psi antikoerper, SNURF antikoerper, SNRPN antikoerper, QflA-11237 antikoerper, QtrA-10022 antikoerper, Sm-N antikoerper, SmN antikoerper, snRNP-N antikoerper, small nuclear ribonucleoprotein polypeptide-like antikoerper, small nuclear ribonucleoprotein polypeptides B and B1 antikoerper, small nuclear ribonucleoprotein polypeptide N antikoerper, small nuclear ribonucleoprotein N antikoerper, small nuclear ribonucleoparticle-associated protein (snRNP) mRNA, clone Sm51 antikoerper, SNRPN upstream reading frame antikoerper, Small nuclear ribonucleoprotein-associated protein N antikoerper, SNRPL antikoerper, snrpb antikoerper, SNRPN antikoerper, Snrpn antikoerper, snrpn antikoerper, SNURF antikoerper
    Hintergrund
    Small Nuclear Ribonucleoprotein Polypeptide N, also called SMN, is a bicistronic imprinted gene that encodes 2 polypeptides, the SmN splicing factor, which is involved in RNA processing, and the SNRPN upstream reading frame (SNURF) polypeptide. The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. SNRPN also encodes a long alternatively spliced transcript containing several small nucleolar RNAs(snoRNAs) and extends downstream to partially overlap the UBE3A gene in the antisense orientation. PWS arises from loss of function of genes in this region expressed exclusively from the paternal chromosome, suggesting that SNRPN may play a role in its etiology. The gene is mapped on 15q11.2. Analysis of maternal DNA and of SNRPN cDNA confirmed that the maternal allele is not expressed in fetal brain and heart. Deletions in the transcription unit of the imprinted gene occur in patients who have PWS or Angelman syndrome because of a parental imprint switch failure in this chromosomal domain.
    UniProt
    P63162
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