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CD53 Antikörper (PE)

CD53 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-53 PE
Produktnummer ABIN303518
  • Target Alle CD53 Antikörper anzeigen
    CD53
    Reaktivität
    • 67
    • 6
    • 5
    Human
    Wirt
    • 43
    • 26
    • 2
    Maus
    Klonalität
    • 46
    • 22
    • 3
    Monoklonal
    Konjugat
    • 31
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD53 Antikörper ist konjugiert mit PE
    Applikation
    • 49
    • 30
    • 27
    • 15
    • 13
    • 13
    • 10
    • 9
    • 9
    • 9
    • 5
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Aufreinigung
    Size-exclusion chromatography
    Immunogen
    Leukocytes of pacient suffering from a LGL-type leukemia
    Klon
    MEM-53
    Isotyp
    IgG1
    Top Product
    Discover our top product CD53 Primärantikörper
  • Applikationshinweise
    Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 10^6 cells in a suspension.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Dilute only prior to immediate use
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody (undiluted) at 2-8 °C. DO NOT FREEZE! Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity.
  • Target
    CD53
    Andere Bezeichnung
    CD53 (CD53 Produkte)
    Hintergrund
    CD53 is a tetraspanin family transmembrane glycoprotein expressed in the lymphoid-myeloid lineage. This molecule has been reported to form complexes with other leukocyte surface proteins such as CD2, CD19, CD21, MHC II, VLA-4 or tetraspanins CD37, CD81 and CD82, thus probably modulating various signaling processes. CD53 is involved in radioresistancy of tumour cells and its triggering has anti-apoptotic effect. In thymus, CD53 is up-regulated in response to positive selection signals during T cell development, and is strongly expressed upon macrophage exposure to bacterial lipopolysaccharide, whereas stimulation of neutrophils results in down-regulation of CD53 expression.Synonyms: Cell surface glycoprotein CD53, Leukocyte surface antigen CD53, MOX44, TSPAN25, Tetraspanin-25
    Gen-ID
    963
    NCBI Accession
    NP_000551
    UniProt
    P19397
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