Vitronectin Antikörper (C-Term)

Produktnummer ABIN3042327

Produktdetails anti-Vitronectin Antikörper

Target: Vitronectin (VTN)

Bindungsspezifität: AA 446-472, C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Vitronectin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Vitronectin(VTN) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequenz: RVNLRTRRVD TVDPPYPRSI AQYWLGC

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Vitronectin(VTN) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: vitronectin
Protein Name: Vitronectin

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Vitronectin (446-472 aa RVNLRTRRVDTVDPPYPRSIAQYWLGC), different from the related mouse sequence by two amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for Vitronectin is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-Vitronectin Antikörper (ABIN3042327)

Zeng, Ma, Chen, Qiu, Wu, Ling, Zeng: "Autocrine fibronectin from differentiating mesenchymal stem cells induces the neurite elongation in vitro and promotes nerve fiber regeneration in transected spinal cord injury." in: Journal of biomedical materials research. Part A, Vol. 104, Issue 8, pp. 1902-11, (2017) (PubMed).

Details zu Vitronectin

Target: Vitronectin (VTN)

Andere Bezeichnung: VTN (VTN Produkte)

Synonyme: VTN antikoerper, DKFZp470F0511 antikoerper, LOC100228142 antikoerper, vtn antikoerper, zgc:112277 antikoerper, V75 antikoerper, VN antikoerper, VNT antikoerper, AI256434 antikoerper, Vn antikoerper, Aa1018 antikoerper, vitronectin antikoerper, vitronectin a antikoerper, vitronectin b antikoerper, vitronectin L homeolog antikoerper, VTN antikoerper, vtn antikoerper, vtna antikoerper, vtnb antikoerper, CpipJ_CPIJ016691 antikoerper, vtn.L antikoerper, Vtn antikoerper

Hintergrund: Vitronectin, also known as VTN, is a protein that in humans is encoded by the VTN gene. The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. Also vitronectin serves to regulate proteolysis initiated by plasminogen activation. In addition, vitronectin is a component of platelets and is, thus, involved in hemostasis.

Synonyms: Complement S Protein antibody|Epibolin antibody|S Protein antibody|S-protein antibody|Serum Spreading Factor antibody|Serum-spreading factor antibody|Somatomedin B antibody| Somatomedin-B antibody|V75 antibody|Vitronectin V10 subunit antibody|Vitronectin V65 subunit antibody|VN antibody|VNT antibody|VTN antibody|VTNC_HUMAN antibody

Gen-ID: 7448

UniProt: P04004

Pathways: Autophagie, Smooth Muscle Cell Migration