TTR Antikörper (AA 21-147)

Produktnummer ABIN3042346

Produktdetails anti-TTR Antikörper

Target: TTR (Transthyretin (TTR))

Bindungsspezifität: AA 21-147

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TTR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Transthyretin(TTR) detection. Tested with WB, IHC-P in Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Transthyretin(TTR) detection. Tested with WB, IHC-P in Mouse,Rat.
Gene Name: transthyretin
Protein Name: Transthyretin

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived rat Prealbumin recombinant protein (Position: G21-N147). Rat Prealbumin shares 94.5% amino acid (aa) sequence identity with mouse Prealbumin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu TTR

Target: TTR (Transthyretin (TTR))

Andere Bezeichnung: TTR (TTR Produkte)

Hintergrund: Transthyretin (TTR) is also known as prealbumin. It is mapped to chromosome region 18q11.2-q12.1. This gene encodes a carrier protein responsible for the transport of thyroid hormones and retinol. The protein consists of a tetramer of identical subunits. Due to increased stability of the tetramer form of this encoded protein in mouse, compared to the human protein, this gene product has a reduced tendency to form amyloid fibrils. In humans, this protein binds beta-amyloid preventing its aggregation and providing a neuroprotective role in Alzheimer's disease.

Synonyms: Amyloid polyneuropathy antibody|Amyloidosis I antibody|ATTR antibody|Carpal tunnel syndrome 1 antibody|CTS antibody|CTS1 antibody| Dysprealbuminemic euthyroidal hyperthyroxinemia antibody|Dystransthyretinemic hyperthyroxinemia antibody|Epididymis luminal protein 111 antibody|HEL111 antibody|HsT2651 antibody|PALB antibody|Prealbumin amyloidosis type I antibody|Prealbumin antibody|Prealbumin Thyroxine-binding antibody|Senile systemic amyloidosis antibody|TBPA antibody|Thyroxine binding prealbumin antibody|Transthyretin antibody|TTHY_HUMAN antibody|TTR antibody|TTR protein antibody

Gen-ID: 24856

UniProt: P02767

Pathways: Hormone Transport