TTR Antikörper (AA 21-147)

Produktnummer ABIN3042346

Produktdetails anti-TTR Antikörper

Target: TTR (Transthyretin (TTR))

Bindungsspezifität: AA 21-147

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TTR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Transthyretin(TTR) detection. Tested with WB, IHC-P in Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Transthyretin(TTR) detection. Tested with WB, IHC-P in Mouse,Rat.
Gene Name: transthyretin
Protein Name: Transthyretin

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived rat Prealbumin recombinant protein (Position: G21-N147). Rat Prealbumin shares 94.5% amino acid (aa) sequence identity with mouse Prealbumin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu TTR

Target: TTR (Transthyretin (TTR))

Andere Bezeichnung: TTR (TTR Produkte)

Synonyme: zgc:103583 antikoerper, TTR antikoerper, LOC100226992 antikoerper, CTS antikoerper, CTS1 antikoerper, HsT2651 antikoerper, PALB antikoerper, TBPA antikoerper, AA408768 antikoerper, AI787086 antikoerper, D17860 antikoerper, prealbumin antikoerper, Lr1 antikoerper, Tbpa antikoerper, Prealbumin antikoerper, xTTR antikoerper, transthyretin (prealbumin, amyloidosis type I) antikoerper, transthyretin antikoerper, Transthyretin antikoerper, transthyretin (prealbumin, amyloidosis type 1) antikoerper, transthyretin-like antikoerper, transthyretin L homeolog antikoerper, ttr antikoerper, TTR antikoerper, vpb38 antikoerper, MRAD2831_RS38185 antikoerper, Caci_4246 antikoerper, LOC100226992 antikoerper, Ttr antikoerper, ttr.L antikoerper

Hintergrund: Transthyretin (TTR) is also known as prealbumin. It is mapped to chromosome region 18q11.2-q12.1. This gene encodes a carrier protein responsible for the transport of thyroid hormones and retinol. The protein consists of a tetramer of identical subunits. Due to increased stability of the tetramer form of this encoded protein in mouse, compared to the human protein, this gene product has a reduced tendency to form amyloid fibrils. In humans, this protein binds beta-amyloid preventing its aggregation and providing a neuroprotective role in Alzheimer's disease.

Synonyms: Amyloid polyneuropathy antibody|Amyloidosis I antibody|ATTR antibody|Carpal tunnel syndrome 1 antibody|CTS antibody|CTS1 antibody| Dysprealbuminemic euthyroidal hyperthyroxinemia antibody|Dystransthyretinemic hyperthyroxinemia antibody|Epididymis luminal protein 111 antibody|HEL111 antibody|HsT2651 antibody|PALB antibody|Prealbumin amyloidosis type I antibody|Prealbumin antibody|Prealbumin Thyroxine-binding antibody|Senile systemic amyloidosis antibody|TBPA antibody|Thyroxine binding prealbumin antibody|Transthyretin antibody|TTHY_HUMAN antibody|TTR antibody|TTR protein antibody

Gen-ID: 24856

UniProt: P02767

Pathways: Hormone Transport