GNB2L1 Antikörper (AA 2-317)
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- Target Alle GNB2L1 Antikörper anzeigen
- GNB2L1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1))
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Bindungsspezifität
- AA 2-317
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GNB2L1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Verwendungszweck
- Rabbit IgG polyclonal antibody for Receptor of activated protein C kinase 1(RACK1) detection. Tested with WB in Human,Mouse,Rat.
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
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Rabbit IgG polyclonal antibody for Receptor of activated protein C kinase 1(RACK1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: receptor for activated C kinase 1
Protein Name: Receptor of activated protein C kinase 1 - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- E.coli-derived human RACK1 recombinant protein (Position: T2-R317). Human RACK1 shares 100% amino acid (aa) sequence identity with both mouse and rat RACK1.
- Isotyp
- IgG
- Top Product
- Discover our top product GNB2L1 Primärantikörper
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- Applikationshinweise
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for RACK1 is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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Overexpressed RACK1 is positively correlated with malignant degree of human colorectal carcinoma." in: Molecular biology reports, Vol. 41, Issue 5, pp. 3393-9, (2015) (PubMed).
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Overexpressed RACK1 is positively correlated with malignant degree of human colorectal carcinoma." in: Molecular biology reports, Vol. 41, Issue 5, pp. 3393-9, (2015) (PubMed).
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- Target
- GNB2L1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1))
- Andere Bezeichnung
- GNB2L1 (GNB2L1 Produkte)
- Synonyme
- MGC53289 antikoerper, GNB2L1 antikoerper, AL033335 antikoerper, GB-like antikoerper, Gnb2-rs1 antikoerper, Rack1 antikoerper, p205 antikoerper, RACK1 antikoerper, H12.3 antikoerper, HLC-7 antikoerper, PIG21 antikoerper, rack1 antikoerper, wu:fb80d08 antikoerper, wu:fk65d12 antikoerper, gnb2-rs1 antikoerper, h12.3 antikoerper, hlc-7 antikoerper, pig21 antikoerper, C12-3 antikoerper, c12.3 antikoerper, guanine nucleotide binding protein, beta 2, related sequence 1 antikoerper, receptor for activated C kinase 1 antikoerper, guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 antikoerper, receptor for activated C kinase 1 L homeolog antikoerper, Guanine nucleotide-binding protein subunit beta-2-like 1 antikoerper, gnb2l1 antikoerper, RACK1 antikoerper, Rack1 antikoerper, rack1.L antikoerper, rack-1 antikoerper
- Hintergrund
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Guanine nucleotide-binding protein subunit beta-2-like 1, also known as RACK1 is a 32 kDa protein that in humans is encoded by the GNB2L1 gene. It is mapped to 5q35.3. GNB2L1 is a major component of translating ribosomes, which harbor significant amounts of PKC. This gene can provide a physical and functional link between PKC signaling and ribosome activation. GNB2L1 is also a mediator of agonist-induced Ca(2+) release. What's more, GNB2L1 is an essential component of an oxygen-independent mechanism for regulating HIF1A stability. Overexpression of GNB2L1 and PKC-alpha suppressed CLOCK-BMAL1 transcriptional activity, and GNB2L1 stimulated phosphorylation of BMAL1 by PKC-alpha in vitro.
Synonyms: Cell proliferation-inducing gene 21 protein antibody|GBLP_HUMAN antibody|Gnb2 rs1 antibody|Gnb2-rs1 antibody|GNB2L1 antibody|Gnb2rs1 antibody|Guanine nucleotide binding protein (G protein) beta polypeptide 2 like 1 antibody|Guanine nucleotide binding protein beta polypeptide 2 like 1 antibody|Guanine nucleotide binding protein beta subunit 2 like 1 antibody|Guanine nucleotide binding protein beta subunit like protein 12.3 antibody|Guanine nucleotide binding protein subunit beta 2 like 1 antibody|Guanine nucleotide binding protein subunit beta like protein 12.3 antibodyGuanine nucleotide-binding protein subunit beta-2-like 1 antibody|Guanine nucleotide-binding protein subunit beta-like protein 12.3 antibody|H12.3 antibody|HLC 7 antibody|HLC-7 antibody|HLC7 antibody|Human lung cancer oncogene 7 protein antibody|Lung cancer oncogene 7 antibody|OTTHUMP00000223704 antibody|OTTHUMP00000223870 antibody|OTTHUMP00000223891 antibody|OTTHUMP00000223893 antibody|OTTHUMP00000223900 antibody|OTTHUMP00000223902 antibody|OTTHUMP00000223930 antibody|OTTHUMP00000223931 antibody|PIG 21 antibody|PIG21 antibody|Proliferation inducing gene 21 antibody|Protein homologous to chicken B complex protein guanine nucleotide binding antibody|RACK 1 antibody|RACK1 antibody|Receptor for activated C kinase antibody|Receptor for activated C kinase 1 antibody|Receptor of activated protein kinase C 1 antibody - Gen-ID
- 10399
- UniProt
- P63244
- Pathways
- cAMP Metabolic Process, Positive Regulation of Endopeptidase Activity
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