GRIK1 Antikörper (AA 271-450)

Produktnummer ABIN3042430

Produktdetails anti-GRIK1 Antikörper

Target: GRIK1 (Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1))

Bindungsspezifität: AA 271-450

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Glutamate receptor ionotropic, kainate 1(GRIK1) detection. Tested with WB in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Glutamate receptor ionotropic, kainate 1(GRIK1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: glutamate receptor, ionotropic, kainate 1
Protein Name: Glutamate receptor ionotropic, kainate 1

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human GRIK1 recombinant protein (Position: R271-I450). Human GRIK1 shares 88% and 94% amino acid (aa) sequences identity with mouse and rat GRIK1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for GRIK1 is approximately 0.2 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu GRIK1

Target: GRIK1 (Glutamate Receptor, Ionotropic, Kainate 1 (GRIK1))

Andere Bezeichnung: GRIK1 (GRIK1 Produkte)

Synonyme: GRIK1 antikoerper, grik1 antikoerper, fv36b03 antikoerper, wu:fv36b03 antikoerper, EAA3 antikoerper, EEA3 antikoerper, GLR5 antikoerper, GLUR5 antikoerper, GluK1 antikoerper, A830007B11Rik antikoerper, D16Ium24 antikoerper, D16Ium24e antikoerper, GluK5 antikoerper, Glur-5 antikoerper, Glur5 antikoerper, Glurbeta1 antikoerper, GluR5 antikoerper, glutamate ionotropic receptor kainate type subunit 1 antikoerper, glutamate receptor, ionotropic, kainate 1a antikoerper, glutamate receptor, ionotropic, kainate 1 antikoerper, GRIK1 antikoerper, grik1a antikoerper, Grik1 antikoerper

Hintergrund: Glutamate receptor, ionotropic, kainate 1, also known as GLUR5, is a protein that in humans is encoded by the GRIK1 gene. It is mapped to 21q21.3. This gene encodes one of the many ionotropic glutamate receptor (GluR) subunits that function as a ligand-gated ion channel. The specific GluR subunit encoded by this gene is of the kainate receptor subtype. Receptor assembly and intracellular trafficking of ionotropic glutamate receptors are regulated by RNA editing and alternative splicing. These receptors mediate excitatory neurotransmission and are critical for normal synaptic function. Exons of this gene are interspersed with exons from the C21or f41 gene, which is transcribed in the same orientation as this gene but does not seem to encode a protein.

Synonyms: EAA3 antibody|EEA3 antibody|Excitatory amino acid receptor 3 antibody|GLR5 antibody|GluR-5 antibody|GluR5 antibody|GluR6 antibody|GluR7 antibody|Glutamate receptor 5 antibody|Glutamate receptor antibody|Glutamate receptor ionotropic kainate 1 antibody|GRIK1 antibody|GRIK1_HUMAN antibody|Human glutamate receptor GLUR5 antibody|ionotropic kainate 1 antibody|OTTHUMP00000096569 antibody

Gen-ID: 2897

UniProt: P39086

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity