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POLH Antikörper (AA 157-361)

POLH Reaktivität: Human, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3042492
  • Target Alle POLH Antikörper anzeigen
    POLH (Polymerase (DNA Directed), eta (POLH))
    Bindungsspezifität
    • 15
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 157-361
    Reaktivität
    • 42
    • 12
    • 11
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte
    Wirt
    • 42
    • 3
    Kaninchen
    Klonalität
    • 44
    • 1
    Polyklonal
    Konjugat
    • 18
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser POLH Antikörper ist unkonjugiert
    Applikation
    • 32
    • 13
    • 13
    • 12
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Verwendungszweck
    Rabbit IgG polyclonal antibody for DNA polymerase eta(POLH) detection. Tested with WB in Human,Rat.
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for DNA polymerase eta(POLH) detection. Tested with WB in Human,Rat.
    Gene Name: polymerase (DNA directed), eta
    Protein Name: DNA polymerase eta
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human POLH recombinant protein (Position: A157-R361). Human POLH shares 93.6% amino acid (aa) sequence identity with mouse POLH.
    Isotyp
    IgG
    Top Product
    Discover our top product POLH Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    POLH (Polymerase (DNA Directed), eta (POLH))
    Andere Bezeichnung
    POLH (POLH Produkte)
    Synonyme
    POLH antikoerper, fc50a12 antikoerper, wu:fc50a12 antikoerper, zgc:136881 antikoerper, zgc:152642 antikoerper, RAD30 antikoerper, RAD30A antikoerper, XP-V antikoerper, XPV antikoerper, polymerase (DNA directed), eta S homeolog antikoerper, DNA polymerase eta antikoerper, polymerase (DNA directed), eta antikoerper, putative DNA polymerase eta antikoerper, polymerase (DNA directed), eta (RAD 30 related) antikoerper, polh.S antikoerper, POLH antikoerper, polh antikoerper, Tb10.70.6190 antikoerper, LINJ_21_0690 antikoerper, Polh antikoerper, LOC100443019 antikoerper
    Hintergrund
    DNA polymerase eta (Pol η), is a protein that in humans is encoded by the POLH gene. This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA, when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene.

    Synonyms: DNA polymerase eta antibody|FLJ16395 antibody|FLJ21978 antibody|Polh antibody|POLH_HUMAN antibody|polymerase DNA directed eta antibody|RAD30 antibody|RAD30 homolog A antibody|RAD30A antibody|Xeroderma pigmentosum variant type protein antibody|XP V antibody|XPV antibody
    Gen-ID
    5429
    UniProt
    Q9Y253
    Pathways
    DNA Reparatur
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