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OPTN Antikörper (AA 241-577)

OPTN Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3042498
  • Target Alle OPTN Antikörper anzeigen
    OPTN (Optineurin (OPTN))
    Bindungsspezifität
    • 15
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 241-577
    Reaktivität
    • 51
    • 31
    • 15
    • 7
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 48
    • 4
    Kaninchen
    Klonalität
    • 50
    • 2
    Polyklonal
    Konjugat
    • 26
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser OPTN Antikörper ist unkonjugiert
    Applikation
    • 43
    • 13
    • 13
    • 11
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Optineurin(OPTN) detection. Tested with WB, IHC-P in Human.
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Optineurin(OPTN) detection. Tested with WB, IHC-P in Human.
    Gene Name: optineurin
    Protein Name: Optineurin
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human Optineurin recombinant protein (Position: R241-I577). Human Optineurin shares 82% amino acid (aa) sequence identity with both mouse and rat Optineurin.
    Isotyp
    IgG
    Top Product
    Discover our top product OPTN Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Optineurin is approximately 0.1 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    OPTN (Optineurin (OPTN))
    Andere Bezeichnung
    OPTN (OPTN Produkte)
    Synonyme
    nrp antikoerper, fip2 antikoerper, hip7 antikoerper, hypl antikoerper, glc1e antikoerper, tfiiia-intp antikoerper, ALS12 antikoerper, FIP2 antikoerper, GLC1E antikoerper, HIP7 antikoerper, HYPL antikoerper, NRP antikoerper, TFIIIA-INTP antikoerper, Fip2 antikoerper, 4930441O07Rik antikoerper, fj52f04 antikoerper, si:ch211-240l19.3 antikoerper, wu:fj52f04 antikoerper, zgc:66386 antikoerper, zgc:77868 antikoerper, optineurin antikoerper, optineurin L homeolog antikoerper, OPTN antikoerper, optn antikoerper, Optn antikoerper, optn.L antikoerper
    Hintergrund
    OPTN is also known as NRP, FIP2 or HYPL. This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.

    Synonyms: 14.7K interacting protein antibody|Ag9 C5 antibody|ALS12 antibody|E3 14.7K interacting protein antibody|E3-14.7K-interacting protein antibody|FIP 2 antibody|FIP-2 antibody|FIP2 antibody|Glaucoma 1 open angle E (adult onset) antibody|Glaucoma 1 open angle E antibody|GLC1E antibody|HIP 7 antibody|HIP-7 antibody|HIP7 antibody|Huntingtin interacting protein 7 antibody|Huntingtin interacting protein HYPL antibody|Huntingtin interacting protein L antibody|Huntingtin yeast partner L antibody|Huntingtin-interacting protein 7 antibody|Huntingtin-interacting protein L antibody|HYPL antibody|Injury inducible protein I 55 antibody|NEMO related protein antibody|NEMO-related protein antibody|NRP antibody|Optic neuropathy inducing protein antibody|Optic neuropathy-inducing protein antibody|Optineurin antibody|OPTN antibody|OPTN_HUMAN antibody|TFIIIA IntP antibody|TFIIIA-IntP antibody|Transcription factor IIIA interacting protein antibody|Transcription factor IIIA-interacting protein antibody|Tumor necrosis factor alpha inducible cellular protein containing leucine zipper domains antibody
    Gen-ID
    10133
    Pathways
    M Phase
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