LOXL1 Antikörper (C-Term)

Produktnummer ABIN3042507

Produktdetails anti-LOXL1 Antikörper

Target: LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))

Bindungsspezifität: AA 397-425, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LOXL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Lysyl oxidase homolog 1(LOXL1) detection. Tested with WB, IHC-P in Human.

Sequenz: AEEKCLASTA YAPEATDYDV RVLLRFPQR

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Lysyl oxidase homolog 1(LOXL1) detection. Tested with WB, IHC-P in Human.
Gene Name: lysyl oxidase-like 1
Protein Name: Lysyl oxidase homolog 1

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human LOXL1 (397-425aa AEEKCLASTAYAPEATDYDVRVLLRFPQR), different from the related mouse sequence by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu LOXL1

Target: LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))

Andere Bezeichnung: LOXL1 (LOXL1 Produkte)

Synonyme: LOL antikoerper, LOXL antikoerper, Loxl antikoerper, si:ch211-238c15.1 antikoerper, lol antikoerper, loxl antikoerper, loxl-1 antikoerper, oxl-1 antikoerper, lysyl oxidase like 1 antikoerper, lysyl oxidase-like 1 antikoerper, lysyl oxidase like 1 L homeolog antikoerper, LOXL1 antikoerper, loxl1 antikoerper, Loxl1 antikoerper, loxl1.L antikoerper

Hintergrund: Lysyl oxidase homolog 1, also known as LOXL1, is an enzyme which in humans is encoded by the LOXL1 gene. This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

Synonyms: Lysyl oxidase like 1 antibody|LOL antibody|LOXL antibody|Lysyl oxidase homolog 1 antibody|Lysyl oxidase like protein 1 antibody

Gen-ID: 4016

UniProt: Q08397