Cx40/GJA5 Antikörper (C-Term)

Produktnummer ABIN3042610

Produktdetails anti-Cx40/GJA5 Antikörper

Target: Cx40/GJA5 (GJA5) (Gap Junction Protein, alpha 5, 40kDa (GJA5))

Bindungsspezifität: AA 341-358, C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cx40/GJA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Gap junction alpha-5 protein(GJA5) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequenz: KRRLSKASSK ARSDDLSV

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Gap junction alpha-5 protein(GJA5) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: gap junction protein, alpha 5, 40 kDa
Protein Name: Gap junction alpha-5 protein

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Connexin 40/GJA5(341-358aa KRRLSKASSKARSDDLSV), identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Predicted Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Cx40/GJA5

Target: Cx40/GJA5 (GJA5) (Gap Junction Protein, alpha 5, 40kDa (GJA5))

Andere Bezeichnung: GJA5 (GJA5 Produkte)

Synonyme: Cx40 antikoerper, 5730555N10Rik antikoerper, Cnx40 antikoerper, Gja-5 antikoerper, ATFB11 antikoerper, CX40 antikoerper, gap junction protein, alpha 5 antikoerper, gap junction protein alpha 5 antikoerper, Gja5 antikoerper, GJA5 antikoerper

Hintergrund: Connexin proteins oligomerize to form intercellular channels, called gap junctions, through which ions and small molecules move between adjacent cells. Connexin 40(Gap junction alpha-5 protein) is a protein that in humans is encoded by the GJA5 gene.This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described.

Synonyms: Connexin 40 antibody|Connexin-40 antibody|Cx40 antibody|CXA5_HUMAN antibody|Gap junction alpha 5 protein antibody|Gap junction alpha-5 protein antibody|Gap junction protein alpha 5 40kD(connexin 40) antibody|Gap junction protein alpha 5 antibody|GJA5 antibody|MGC11185 antibody

UniProt: P36382

Pathways: Cell-Cell Junction Organization