GJB1 Antikörper (Middle Region)
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- Target Alle GJB1 Antikörper anzeigen
- GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))
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Bindungsspezifität
- AA 215-231, Middle Region
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GJB1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Verwendungszweck
- Rabbit IgG polyclonal antibody for Gap junction beta-1 protein(GJB1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- Sequenz
- RACARRAQRR SNPPSRK
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
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Rabbit IgG polyclonal antibody for Gap junction beta-1 protein(GJB1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: gap junction protein, beta 1, 32 kDa
Protein Name: Gap junction beta-1 protein - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence in the middle region of human Connexin 32/GJB1(215-231aa RACARRAQRRSNPPSRK), identical to the related mouse and rat sequences.
- Isotyp
- IgG
- Top Product
- Discover our top product GJB1 Primärantikörper
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- Applikationshinweise
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Konservierungsmittel
- Thimerosal (Merthiolate), Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - Haltbarkeit
- 12 months
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- Target
- GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))
- Andere Bezeichnung
- GJB1 (GJB1 Produkte)
- Synonyme
- GJIC antikoerper, cmtx antikoerper, cmtx1 antikoerper, connexin-30 antikoerper, connexin32 antikoerper, cx30 antikoerper, cx32 antikoerper, gja1 antikoerper, CX32 antikoerper, GJB1 antikoerper, AI118175 antikoerper, Cnx32 antikoerper, Cx32 antikoerper, Gjb-1 antikoerper, CMTX antikoerper, CMTX1 antikoerper, gjb1-a antikoerper, gap junction protein beta 1 antikoerper, connexin 32 antikoerper, probable serine/threonine-protein kinase CST antikoerper, gap junction protein, beta 1 antikoerper, gap junction protein beta 1 L homeolog antikoerper, gjb1 antikoerper, CX32 antikoerper, LOC9303136 antikoerper, GJB1 antikoerper, Gjb1 antikoerper, gjb1.L antikoerper
- Hintergrund
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Connexins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells(Bergoffen et al., 1993). For a general discussion of connexin proteins, also known as Gap junction beta-1 protein. Gap junction beta-1 protein is a protein that in humans is encoded by the GJB1 gene. In melanocytic cells GJB1 gene expression may be regulated by MITF.
Synonyms: Charcot Marie Tooth neuropathy X linked antibody|CMTX 1 antibody|CMTX antibody|CMTX1 antibody|Connexin-32 antibody|Connexin32 antibody|CX 32 antibody|CX32 antibody|CXB1_HUMAN antibody|GAP junction 28 kDa liver protein antibody|Gap junction beta 1 protein antibody|Gap junction beta-1 protein antibody|Gap junction protein beta 1 32kD antibody|Gap junction protein beta 1 antibody|GJB 1 antibody|GJB1 antibody - UniProt
- P08034
- Pathways
- Cell-Cell Junction Organization
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