CTH Antikörper (C-Term)

Produktnummer ABIN3042672

Produktdetails anti-CTH Antikörper

Target: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Bindungsspezifität: AA 316-331, C-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Cystathionine gamma-lyase(CTH) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequenz: FYIKGTLQHA EIFLKN

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Cystathionine gamma-lyase(CTH) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: cystathionase(cystathionine gamma-lyase)
Protein Name: Cystathionine gamma-lyase

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Cystathionase(316-331aa FYIKGTLQHAEIFLKN), different from the related mouse and rat sequences by two amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Referenzen für anti-CTH Antikörper (ABIN3042672)

Liu, Li, Liang, Li, Jiang, Chu, Yang: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." in: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).

Qi, Zhao, Li, Shao, Wang, Sui, Yu, Shao, Gui, Li, Jia, Jiang, Li, Zhang, Wang, Wang: "High C-X-C motif chemokine 5 expression is associated with malignant phenotypes of prostate cancer cells via autocrine and paracrine pathways." in: International journal of oncology, Vol. 53, Issue 1, pp. 358-370, (2018) (PubMed).

Shi, Guo, Shi, Yu, Song, Li: "Caffeic Acid Phenethyl Ester inhibit Hepatic Fibrosis by Nitric Oxide Synthase and Cystathionine Gamma-Lyase in Rats." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 21, pp. 2774-80, (2016) (PubMed).

Chen, Wang, Li, Jiang, Lu, Zhou: "Heme Oxygenase-1 Promotes Delayed Wound Healing in Diabetic Rats." in: Journal of diabetes research, Vol. 2016, pp. 9726503, (2016) (PubMed).

Guo, Duan, Wang, Zhou, Li, Sun: "Endogenous carbon monoxide downregulates hepatic cystathionine-γ-lyase in rats with liver cirrhosis." in: Experimental and therapeutic medicine, Vol. 10, Issue 6, pp. 2039-2046, (2015) (PubMed).

Details zu CTH

Target: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Andere Bezeichnung: CTH (CTH Produkte)

Synonyme: DYT17 antikoerper, DYT18 antikoerper, DYT9 antikoerper, EIG12 antikoerper, GLUT antikoerper, GLUT1 antikoerper, GLUT1DS antikoerper, HTLVR antikoerper, PED antikoerper, wu:fb48e03 antikoerper, wu:fb58d08 antikoerper, zgc:66001 antikoerper, zgc:85785 antikoerper, CTH antikoerper, 0610010I13Rik antikoerper, AI314617 antikoerper, BC019483 antikoerper, CSE antikoerper, Cys3 antikoerper, cysA antikoerper, SCQ11.03c antikoerper, DDBDRAFT_0190313 antikoerper, DDBDRAFT_0191318 antikoerper, DDB_0190313 antikoerper, DDB_0191318 antikoerper, H antikoerper, MGC75946 antikoerper, cystathionine gamma-lyase antikoerper, solute carrier family 2 member 1 antikoerper, cystathionase (cystathionine gamma-lyase) antikoerper, cystathionine gamma-lyase L homeolog antikoerper, CTH antikoerper, SLC2A1 antikoerper, cth antikoerper, Cth antikoerper, SCO3920 antikoerper, mlr1566 antikoerper, TA_RS00415 antikoerper, MAP_RS15640 antikoerper, SPO3344 antikoerper, CNN01730 antikoerper, Mmcs_1928 antikoerper, RHA1_RS31820 antikoerper, HNE_1212 antikoerper, MAV_3867 antikoerper, MSMEG_2394 antikoerper, Mvan_2142 antikoerper, SACE_6136 antikoerper, Mflv_4220 antikoerper, cysA antikoerper, cth.L antikoerper

Hintergrund: Cystathionine gamma-lyase(or cystathionase) is an enzyme which breaks down cystathionine into cysteine and alpha-ketobutyrate. The International Radiation Hybrid Mapping Consortium mapped the CTH gene to chromosome 1. The CTH gene had earlier been assigned to chromosome 16 by study of somatic cell hybrids. It is demonstrated that hydrogen sulfide(H2S) is physiologically generated by CTH.

Synonyms: CGL_HUMAN antibody|CTH antibody|cystathionase(cystathionine gamma-lyase) antibody|Cystathionine gamma lyase antibody|Cystathionine gamma-lyase antibody|Cysteine desulfhydrase antibody|Gamma cystathionase antibody|Gamma-cystathionase antibody|Homoserine deaminase antibody|Homoserine dehydratase antibody|MGC9471 antibody

UniProt: P32929

Pathways: ER-Nucleus Signaling, Warburg Effekt