Caveolin 2 Antikörper (N-Term)

Produktnummer ABIN3042683

Produktdetails anti-Caveolin 2 Antikörper

Target: Caveolin 2 (CAV2)

Bindungsspezifität: AA 1-17, N-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caveolin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Caveolin-2(CAV2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequenz: MGLETEKADV QLFMDDD

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Caveolin-2(CAV2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: caveolin 2
Protein Name: Caveolin-2

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Caveolin-2(1-17aa MGLETEKADVQLFMDDD), different from the related rat and mouse sequences by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Referenzen für anti-Caveolin 2 Antikörper (ABIN3042683)

Wang, Zhao, Wu, He, Qu, Zhao, Zhao, Li, Wang: "Mechanistic analysis of taxol-induced multidrug resistance in an ovarian cancer cell line." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 14, Issue 9, pp. 4983-8, (2013) (PubMed).

Details zu Caveolin 2

Target: Caveolin 2 (CAV2)

Andere Bezeichnung: CAV2 (CAV2 Produkte)

Synonyme: CAV antikoerper, AI447843 antikoerper, cav-2 antikoerper, zgc:86696 antikoerper, wu:fc52e01 antikoerper, caveolin-2 antikoerper, CAV-2 antikoerper, Caveolin-2 antikoerper, Cav-2 antikoerper, cav antikoerper, cav2 antikoerper, caveolin 2 antikoerper, caveolin 2 L homeolog antikoerper, caveolin-2 antikoerper, Caveolin-2 antikoerper, CAV2 antikoerper, Cav2 antikoerper, cav2.L antikoerper, cav2 antikoerper, LOC100093133 antikoerper, cav-2 antikoerper

Hintergrund: Caveolin-2 is a protein related to caveolin-1 which is derived caveolin-enriched membranes. CAV2 and CAV1 are similar in most respects and they differ in their functional interactions with heterotrimeric G proteins. Caveolin-1 and caveolin-2 are expressed in neuronal cells. Caveolin-2 was upregulated in response to neuronal cell injury. The CAV2 gene is mapped to 7q31.1-q31.2. The CAV1 gene contains 3 exons, while the human CAV2 gene contains 2 exons. The boundary of the last exon of CAV1 and CAV2 are analogous, suggesting that they arose through gene duplication. The genes encoding murine caveolin-1 and -2 are colocalized within the A2 region of mouse chromosome 6.

Synonyms: CAV antibody|CAV2 antibody|CAV2_HUMAN antibody|Caveolae protein 20 kD antibody|Caveolin 2 antibody|Caveolin 2 isoform a and b antibody|Caveolin-2 antibody|MGC12294 antibody|OTTHUMP00000025032 antibody|OTTHUMP00000195982 antibody

UniProt: P51636

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development