CDK9 Antikörper (AA 141-372)

Produktnummer ABIN3042745

Produktdetails anti-CDK9 Antikörper

Target: CDK9 (Cyclin-Dependent Kinase 9 (CDK9))

Bindungsspezifität: AA 141-372

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Cyclin-dependent kinase 9(CDK9) detection. Tested with WB, IHC-P in Human,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Cyclin-dependent kinase 9(CDK9) detection. Tested with WB, IHC-P in Human,Rat.
Gene Name: cyclin-dependent kinase 9
Protein Name: Cyclin-dependent kinase 9

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Cdk9 recombinant protein (Position: H141-F372). Human Cdk9 shares 99.1% amino acid (aa) sequence identity with both mouse and rat Cdk9.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu CDK9

Target: CDK9 (Cyclin-Dependent Kinase 9 (CDK9))

Andere Bezeichnung: CDK9 (CDK9 Produkte)

Synonyme: C-2k antikoerper, CDC2L4 antikoerper, CTK1 antikoerper, PITALRE antikoerper, TAK antikoerper, wu:fb22e09 antikoerper, wu:fc06c02 antikoerper, c-2k antikoerper, cdc2l4 antikoerper, cdk9 antikoerper, ctk1 antikoerper, pitalre antikoerper, tak antikoerper, CDK9 antikoerper, CG5179 antikoerper, Dmel\\CG5179 antikoerper, P-TEF antikoerper, P-TEFb antikoerper, PTefb antikoerper, cyclin dependent kinase 9 antikoerper, cyclin-dependent kinase 9 (CDC2-related kinase) antikoerper, cyclin-dependent kinase 9 L homeolog antikoerper, cyclin-dependent kinase 9 antikoerper, Cyclin-dependent kinase 9 antikoerper, cyclin-dependent kinase 9 S homeolog antikoerper, CDK9 antikoerper, cdk9 antikoerper, cdk9.L antikoerper, Cdk9 antikoerper, cdk9.S antikoerper

Hintergrund: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.

Synonyms: C 2k antibody|C-2K antibody|CDC2 related kinase antibody|CDC2L4 antibody|Cdk 9 antibody| Cdk9 antibody|CDK9_HUMAN antibody|Cell division cycle 2 like protein kinase 4 antibody|Cell division cycle 2-like protein kinase 4 antibody|Cell division protein kinase 9 antibody| CTK1 antibody|Cyclin dependent kinase 9 antibody|Cyclin-dependent kinase 9 antibody|PITALRE antibody|Serine threonine protein kinase PITALRE antibody|Serine/threonine-protein kinase PITALRE antibody|TAK antibody|Tat associated kinase complex catalytic subunit antibody

Gen-ID: 1025

UniProt: P50750

Pathways: Zellzyklus