IL-10 Antikörper (AA 19-178)
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- Target Alle IL-10 (IL10) Antikörper anzeigen
- IL-10 (IL10) (Interleukin 10 (IL10))
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Bindungsspezifität
- AA 19-178
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Reaktivität
- Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IL-10 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Verwendungszweck
- Rabbit IgG polyclonal antibody for Interleukin-10(IL10) detection. Tested with WB, IHC-P, ELISA in Rat.
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
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Rabbit IgG polyclonal antibody for Interleukin-10(IL10) detection. Tested with WB, IHC-P, ELISA in Rat.
Gene Name: interleukin 10
Protein Name: Interleukin-10(IL-10) - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- E. coli-derived rat IL-10 recombinant protein(Position: S19-N178).
- Isotyp
- IgG
- Top Product
- Discover our top product IL10 Primärantikörper
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- Applikationshinweise
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WB: Concentration: 0.1-0.5 μg/mL, Species: Rat
IHC-P: Concentration: 0.5-1 μg/mL, Species: Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Species: Rat
Notes: Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - Haltbarkeit
- 12 months
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Myocardial ischemic post-conditioning protects the lung against myocardial ischemia/reperfusion-induced damage by activating GSK-3β." in: Acta cirurgica brasileira, Vol. 32, Issue 5, pp. 376-387, (2017) (PubMed).
: "Re-polarizing Myeloid-derived Suppressor Cells (MDSCs) with Cationic Polymers for Cancer Immunotherapy." in: Scientific reports, Vol. 6, pp. 24506, (2017) (PubMed).
: "Women with recurrent spontaneous abortion have decreased 25(OH) vitamin D and VDR at the fetal-maternal interface." in: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, Vol. 50, Issue 11, pp. e6527, (2017) (PubMed).
: "The role of glycogen synthase kinase 3 beta in brain injury induced by myocardial ischemia/reperfusion injury in a rat model of diabetes mellitus." in: Neural regeneration research, Vol. 12, Issue 10, pp. 1632-1639, (2017) (PubMed).
: "Bufei Yishen Granules Combined with Acupoint Sticking Therapy Suppress Inflammation in Chronic Obstructive Pulmonary Disease Rats: Via JNK/p38 Signaling Pathway." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2017, pp. 1768243, (2017) (PubMed).
: "Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats." in: Nutrients, Vol. 7, Issue 6, pp. 4829-50, (2016) (PubMed).
: "Pentoxifylline inhibits pulmonary inflammation induced by infrarenal aorticcross-clamping dependent of adenosine receptor A2A." in: American journal of translational research, Vol. 8, Issue 5, pp. 2210-21, (2016) (PubMed).
: "Evaluation of the probiotic properties of new Lactobacillus and Bifidobacterium strains and their in vitro effect." in: Applied microbiology and biotechnology, Vol. 99, Issue 13, pp. 5613-26, (2015) (PubMed).
: "IL-10 and IL-1? mediate neuropathic-pain like behavior in the ventrolateral orbital cortex." in: Neurochemical research, Vol. 40, Issue 4, pp. 733-9, (2015) (PubMed).
: "Inhibition of Tumor Growth and Immunomodulatory Effects of Flavonoids and Scutebarbatines of Scutellaria barbata D. Don in Lewis-Bearing C57BL/6 Mice." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 630760, (2015) (PubMed).
: "Putative role of ischemic postconditioning in a rat model of limb ischemia and reperfusion: involvement of hypoxia-inducible factor-1? expression." in: Brazilian journal of medical and biological research = Revista brasileira de pesquisas me?dicas e biolo?gicas / Sociedade Brasileira de Biofi?sica ... [et al.], Vol. 47, Issue 9, pp. 738-45, (2014) (PubMed).
: "Exogenous interleukin-10 alleviates allergic inflammation but inhibits local interleukin-10 expression in a mouse allergic rhinitis model." in: BMC immunology, Vol. 15, pp. 9, (2014) (PubMed).
: "Protective roles of quercetin in acute myocardial ischemia and reperfusion injury in rats." in: Molecular biology reports, Vol. 39, Issue 12, pp. 11005-9, (2012) (PubMed).
: "Interleukin-10 of red nucleus plays anti-allodynia effect in neuropathic pain rats with spared nerve injury." in: Neurochemical research, Vol. 37, Issue 8, pp. 1811-9, (2012) (PubMed).
: "Effects of penehyclidine hydrochloride in small intestinal damage caused by limb ischemia-reperfusion." in: World journal of gastroenterology, Vol. 17, Issue 2, pp. 254-9, (2011) (PubMed).
: "Increased IL-10 mRNA expression in tumor-associated macrophage correlated with late stage of lung cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 30, pp. 62, (2011) (PubMed).
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Myocardial ischemic post-conditioning protects the lung against myocardial ischemia/reperfusion-induced damage by activating GSK-3β." in: Acta cirurgica brasileira, Vol. 32, Issue 5, pp. 376-387, (2017) (PubMed).
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- Target
- IL-10 (IL10) (Interleukin 10 (IL10))
- Andere Bezeichnung
- IL10 (IL10 Produkte)
- Synonyme
- CSIF antikoerper, GVHDS antikoerper, IL-10 antikoerper, IL10A antikoerper, TGIF antikoerper, Il-10 antikoerper, IL10X antikoerper, interleukin 10 antikoerper, IL10 antikoerper, Il10 antikoerper
- Hintergrund
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Interleukin-10(IL-10 or IL10), also known as human cytokine synthesis inhibitory factor(CSIF), is an anti-inflammatory cytokine. In humans IL-10 is encoded by the IL10 gene. It is capable of inhibiting synthesis of pro-inflammatory cytokines like IFN-gamma, IL-2, IL-3, TNFalpha and GM-CSF made by cells such as macrophages and regulatory T-cells.IL-10 also displays potent abilities to suppress the antigen presentation capacity of antigen presenting cells. Kim et al.(1992) showed that the mouse IL 10 gene contains 5 exons and spans about 5.2 kb of genomic DNA. Eskdale et al.(1997) mapped the IL10 gene to the junction between 1q31 and 1q32.
Synonyms: CSIF antibody|Cytokine Synthesis Inhibitory Factor antibody|GVHDS antibody|IL 10 antibody|IL-10 antibody|IL10 antibody|IL10A antibody|Interleukin 10 antibody|Interleukin-10 antibody|Interleukin10 antibody|MGC126450 antibody|MGC126451 antibody|T-cell growth inhibitory factor antibody|TGIF antibody - UniProt
- P29456
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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