Factor VIII Antikörper (Middle Region)

Produktnummer ABIN3042924

Produktdetails anti-Factor VIII Antikörper

Target: Factor VIII (F8) (Coagulation Factor VIII (F8))

Bindungsspezifität: AA 1264-1278, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Factor VIII Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Coagulation factor VIII(F8) detection. Tested with WB in Human.

Sequenz: APVLQDFRSL NDSTN

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Coagulation factor VIII(F8) detection. Tested with WB in Human.
Gene Name: coagulation factor VIII, procoagulant component
Protein Name: Coagulation factor VIII

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Factor VIII(1264-1278aa APVLQDFRSLNDSTN).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Referenzen für anti-Factor VIII Antikörper (ABIN3042924)

Zhang, Shen: "A ferulic acid (FA)-eluting system for biodegradable magnesium stent: Cells response of HUVECs." in: Journal of biomedical materials research. Part A, Vol. 103, Issue 8, pp. 2758-69, (2015) (PubMed).

Li, Cao, Zeng, Liang, Xue, Xi, Zhou, Jiang: "Angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis prevents lipopolysaccharide-induced apoptosis of pulmonary microvascular endothelial cells by inhibiting JNK/NF-?B pathways." in: Scientific reports, Vol. 5, pp. 8209, (2015) (PubMed).

Wu, Chen, Guo, He, Hu: "Effects of transforming growth factor-?2 on myocilin expression and secretion in human primary cultured trabecular meshwork cells." in: International journal of clinical and experimental pathology, Vol. 7, Issue 8, pp. 4827-36, (2014) (PubMed).

Wang, Chen, Lin, Jia, Tian, Yang, Zhao, Lai, Jiang, Sun, Zhong, Ran, Lu: "Effects of chronic exposure to cigarette smoke on canonical transient receptor potential expression in rat pulmonary arterial smooth muscle." in: American journal of physiology. Cell physiology, Vol. 306, Issue 4, pp. C364-73, (2014) (PubMed).

Zhang, Shen, Xu, Hu, Chen, Chi, Kong, Li, Li, Guo, Xiong, Zhang: "Cardiomyocyte differentiation induced in cardiac progenitor cells by cardiac fibroblast-conditioned medium." in: Experimental biology and medicine (Maywood, N.J.), Vol. 239, Issue 5, pp. 628-37, (2014) (PubMed).

Huang, Li, Qi, Zhang, Zhang, Wang, Zhang, Gui: "Coordinated regulation of autophagy and apoptosis determines endothelial cell fate during Dengue virus type 2 infection." in: Molecular and cellular biochemistry, Vol. 397, Issue 1-2, pp. 157-65, (2014) (PubMed).

Pan, Chen, Huang, Yao, Ma: "Transforming growth factor ?1 induces the expression of collagen type I by DNA methylation in cardiac fibroblasts." in: PLoS ONE, Vol. 8, Issue 4, pp. e60335, (2013) (PubMed).

Liu, Zhang, Hou, Wang, Yang, Guan, Dong, Gao, Feng: "Vascularized bone tissue formation induced by fiber-reinforced scaffolds cultured with osteoblasts and endothelial cells." in: BioMed research international, Vol. 2013, pp. 854917, (2013) (PubMed).

Jiang, Deng, Duan, Chen, Xiang, Lu, Ma: "Somatostatin receptors SSTR2 and SSTR5 are expressed in the human thoracic duct." in: Lymphology, Vol. 44, Issue 1, pp. 21-8, (2011) (PubMed).

Zhou, Zhan, Zhou, Li, Lin, Tang, Shu, Chen, Zeng, Cai, Jiang: "A study of the distribution and density of the VEGFR-2 receptor on glioma microvascular endothelial cell membranes." in: Cellular and molecular neurobiology, Vol. 31, Issue 5, pp. 687-94, (2011) (PubMed).

You, Sun, Wang, Chen, Luo: "Role of src-suppressed C kinase substrate in rat pulmonary microvascular endothelial hyperpermeability stimulated by inflammatory cytokines." in: Inflammation research : official journal of the European Histamine Research Society ... [et al.], Vol. 59, Issue 11, pp. 949-58, (2010) (PubMed).

You, Sun, Wang, Shen, Wang: "Interleukin-17F-induced pulmonary microvascular endothelial monolayer hyperpermeability via the protein kinase C pathway." in: The Journal of surgical research, Vol. 162, Issue 1, pp. 110-21, (2010) (PubMed).

Li, Qu, Hao, Sun, Guo, Guo, Sun, Tu: "Proteomic analysis of primary porcine endothelial cells after infection by classical swine fever virus." in: Biochimica et biophysica acta, Vol. 1804, Issue 9, pp. 1882-8, (2010) (PubMed).

Feng, Peng, Li, Zhou, Li, Ling, Wei, Tian: "Identification and characterization of cancer stem-like cells from primary carcinoma of the cervix uteri." in: Oncology reports, Vol. 22, Issue 5, pp. 1129-34, (2009) (PubMed).

Hao, Yu, Li, Shi, Li, Hao: "Inhibitory effect of antisense vascular endothelial growth factor RNA on the profile of hepatocellular carcinoma cell line in vitro and in vivo." in: World journal of gastroenterology, Vol. 12, Issue 7, pp. 1140-3, (2006) (PubMed).

Details zu Factor VIII

Target: Factor VIII (F8) (Coagulation Factor VIII (F8))

Andere Bezeichnung: F8 (F8 Produkte)

Synonyme: fb61d02 antikoerper, wu:fb61d02 antikoerper, Cf-8 antikoerper, Cf8 antikoerper, FVIII antikoerper, AHF antikoerper, DXS1253E antikoerper, F8B antikoerper, F8C antikoerper, HEMA antikoerper, coagulation factor VIIi antikoerper, coagulation factor VIII antikoerper, coagulation factor VIII, procoagulant component antikoerper, f7i antikoerper, F8 antikoerper

Hintergrund: Coagulation Factor VIII(FVIII) is an essential blood-clotting protein, also known as anti-hemophilic factor(AHF). By in situ hybridization, Tantravahi et al.(1986) concluded that the F8 gene is located in the proximal part of chromosome Xq28 with probes DX13 and St14 distally located. The F8 gene encodes coagulation factor VIII, a large plasma glycoprotein that functions in the blood coagulation cascade as a cofactor for the factor IXa-dependent activation of factor X(F10). Factor VIII is activated proteolytically by a variety of coagulation enzymes, including thrombin(F2). Factor VIII is tightly associated in the blood with von Willebrand factor(VWF), which serves as a protective carrier protein for factor VIII(Toole et al., 1984, Hoyer, 1994).

Synonyms: Ahf antibody|Antihemophilic factor antibody|Coagulation factor VIII antibody|Coagulation factor VIII associated protein b antibody|Coagulation factor VIII isoform b antibody|Coagulation factor VIII procoagulent component antibody|coagulation factor VIII, procoagulant component antibody|Coagulation factor VIIIc antibody|Dna segment on chromosome x unique 1253 expressed sequence antibody|Dxs1253e antibody|F8 antibody|F8 protein antibody|F8b antibody|F8c antibody|FA8_HUMAN antibody|Factor VIII F8b antibody|Factor VIIIa light chain antibody|FactorVIII antibody|FVIII antibody|Hema antibody|Hema coagulation factor VIIIc procoagulent component antibody|Hemophilia a antibody|Hemophilia classic antibody|Hemophilia, classic antibody|OTTHUMP00000061446 antibody|OTTHUMP00000196174 antibody|Procoagulant component antibody

UniProt: P00451