Prothrombin Antikörper (C-Term)
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- Target Alle Prothrombin (F2) Antikörper anzeigen
- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
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Bindungsspezifität
- AA 600-612, C-Term
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Reaktivität
- Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Prothrombin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Verwendungszweck
- Rabbit IgG polyclonal antibody for Prothrombin(F2) detection. Tested with WB in Rat.
- Sequenz
- THVFRLKRWM QKV
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
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Rabbit IgG polyclonal antibody for Prothrombin(F2) detection. Tested with WB in Rat.
Gene Name: coagulation factor II(thrombin)
Protein Name: Prothrombin - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of rat Prothrombin(600-612aa THVFRLKRWMQKV).
- Isotyp
- IgG
- Top Product
- Discover our top product F2 Primärantikörper
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- Applikationshinweise
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Konservierungsmittel
- Thimerosal (Merthiolate), Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - Haltbarkeit
- 12 months
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Heparin impairs angiogenesis through inhibition of microRNA-10b." in: The Journal of biological chemistry, Vol. 286, Issue 30, pp. 26616-27, (2011) (PubMed).
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Heparin impairs angiogenesis through inhibition of microRNA-10b." in: The Journal of biological chemistry, Vol. 286, Issue 30, pp. 26616-27, (2011) (PubMed).
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- Target
- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
- Andere Bezeichnung
- F2 (F2 Produkte)
- Synonyme
- PT antikoerper, RPRGL2 antikoerper, THPH1 antikoerper, Cf-2 antikoerper, Cf2 antikoerper, FII antikoerper, thrombin antikoerper, zgc:66319 antikoerper, wu:fb57c10 antikoerper, wu:fd42e09 antikoerper, wu:fd59d01 antikoerper, prothrombin antikoerper, F2 antikoerper, coagulation factor II, thrombin antikoerper, coagulation factor II antikoerper, coagulation factor II (thrombin) antikoerper, F2 antikoerper, f2 antikoerper
- Hintergrund
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F2(Coagulation Factor II), also known as thrombin, is a serine protease that in humans is encoded by the F2 gene. Royle et al.(1987) assigned the gene for human prothrombin(F2) to chromosome 11p11-q12 by analysis of a panel of somatic cell hybrid DNAs and by in situ hybridization, using both cDNA and genomic probes. The activated thrombin enzyme plays an important role in hemostasis and thrombosis: it converts fibrinogen to fibrin for blood clot formation, stimulates platelet aggregation, and activates coagulation factors V, VIII(F8), and XIII(F13A1). Thrombin also inhibits coagulation by activating protein C.
Synonyms: coagulation factor II(thrombin) antibody|Coagulation factor II antibody|Coagulation factor II precursor antibody|Coagulation factor II thrombin antibody|Dysprothrombinemia antibody|EC 3.4.21.5 antibody|F 2 antibody|F2 antibody|Factor II antibody|Hyperprothrombinemia antibody|Hypoprothrombinemia antibody|Prepro coagulation factor II antibody|Prothrombin antibody|Prothrombin B chain antibody|prothrombin B-chain antibody|PT antibody|RPRGL2 antibody|Serine protease antibody|THPH1 antibody|THRB antibody|THRB_HUMAN antibody|Thrombin antibody|Thrombin heavy chain antibody - UniProt
- P18292
- Pathways
- Komplementsystem, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling
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