IDS Antikörper (C-Term)

Produktnummer ABIN3042998

Produktdetails anti-IDS Antikörper

Target: IDS (Iduronate 2-Sulfatase (IDS))

Bindungsspezifität: AA 430-448, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IDS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Iduronate 2-sulfatase(IDS) detection. Tested with WB, IHC-P in Human.

Sequenz: ELCREGKNLL KHFRFRDLE

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Iduronate 2-sulfatase(IDS) detection. Tested with WB, IHC-P in Human.
Gene Name: iduronate 2-sulfatase
Protein Name: Iduronate 2-sulfatase

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Iduronate 2 sulfatase(430-448aa ELCREGKNLLKHFRFRDLE).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu IDS

Target: IDS (Iduronate 2-Sulfatase (IDS))

Andere Bezeichnung: IDS (IDS Produkte)

Synonyme: mps2 antikoerper, sids antikoerper, zgc:158245 antikoerper, MPS2 antikoerper, SIDS antikoerper, AW214631 antikoerper, iduronate 2-sulfatase antikoerper, IDS antikoerper, CpipJ_CPIJ004938 antikoerper, ids antikoerper, Ids antikoerper

Hintergrund: IDS(Iduronate-2-sulfatase) is a sulfatase enzyme associated with Hunter syndrome. Iduronate 2-sulfatase is involved in the lysosomal degradation of the glycosaminoglycans heparan sulfate and dermatan sulfate. Wilson et al.(1991) used an IDS cDNA clone to localize the gene to Xq28, distal to the fragile X site. Faust et al.(1992) and Daniele et al.(1993) demonstrated that the homologous Ids gene in the mouse occupies the same position on the X chromosome in relation to the FMR1, F9, and GABRA3 genes. Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked mucopolysaccharidosis type II, also known as Hunter syndrome. Iduronate-2-sulfatase has a strong sequence homology with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase.

Synonyms: Alpha L iduronate sulfate sulfatase antibody|Alpha-L-iduronate sulfate sulfatase antibody|AW214631 antibody|Ids antibody|IDS_HUMAN antibody|Iduronate 2 sulfatase 14 kDa chain antibody|Iduronate 2 sulfatase 42 kDa chain antibody|Iduronate 2 sulfatase antibody|Iduronate 2-sulfatase 14 kDa chain antibody|Iduronate sulfatase antibody|Idursulfase antibody|MPS2 antibody|RP23-29M4.1 antibody|SIDS antibody

UniProt: P22304

Pathways: Glycosaminoglycan Metabolic Process