HMGB4 Antikörper (N-Term)

Produktnummer ABIN3043021

Produktdetails anti-HMGB4 Antikörper

Target: HMGB4 (High Mobility Group Box 4 (HMGB4))

Bindungsspezifität: AA 24-41, N-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMGB4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for High mobility group protein B4(HMGB4) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: RNKFKEQQPN TYVGFKEF

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for High mobility group protein B4(HMGB4) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: high mobility group box 4
Protein Name: High mobility group protein B4

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human HMGB4(24-41aa RNKFKEQQPNTYVGFKEF), different from the related mouse and rat sequences by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-HMGB4 Antikörper (ABIN3043021)

Rouhiainen, Zhao, Vanttola, Qian, Kulesskiy, Kuja-Panula, Gransalke, Grönholm, Unni, Meistrich, Tian, Auvinen, Rauvala: "HMGB4 is expressed by neuronal cells and affects the expression of genes involved in neural differentiation." in: Scientific reports, Vol. 6, pp. 32960, (2018) (PubMed).

Zhao, Xue, Wang: "HMGB1, TGF-β and NF-κB are associated with chronic allograft nephropathy." in: Experimental and therapeutic medicine, Vol. 14, Issue 6, pp. 6138-6146, (2017) (PubMed).

Details zu HMGB4

Target: HMGB4 (High Mobility Group Box 4 (HMGB4))

Andere Bezeichnung: HMGB4 (HMGB4 Produkte)

Synonyme: HMGB4 antikoerper, dJ1007G16.5 antikoerper, 1700001F22Rik antikoerper, AI326135 antikoerper, high mobility group box 4 antikoerper, high-mobility group box 4 antikoerper, HMGB4 antikoerper, Hmgb4 antikoerper

Hintergrund: HMGB4 is HMG2 like, isoform 2, high-mobility group box 4. This gene can be found on Chromosome 1. HMGB4 contains two HMG-box regions, which is found in a variety of eukaryotic chromosomal proteins and transcription. HMGB proteins are phosphorylated to various extents reveals that the existence of differentially modified forms increases the number of distinct HMGB protein variants in plant chromatin that may be adapted to certain functions.

Synonyms: High mobility group box 4 antibody|High mobility group protein B4 antibody|HMG2 like antibody