Neurotrophin 3 Antikörper (Middle Region)

Produktnummer ABIN3043024

Produktdetails anti-Neurotrophin 3 Antikörper

Target: Neurotrophin 3 (NTF3)

Bindungsspezifität: AA 174-189, Middle Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neurotrophin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Neurotrophin-3(NTF3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequenz: TVLGEIKTGN SPVKQY

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Neurotrophin-3(NTF3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: neurotrophin 3
Protein Name: Neurotrophin-3(NT-3)

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Neurotrophin 3(174-189aa TVLGEIKTGNSPVKQY), identical to the related rat and mouse sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-Neurotrophin 3 Antikörper (ABIN3043024)

Guo, Zeng, Li, Huang, Liu, Li, Ding, Wu, Cai: "Cotransplant of neural stem cells and NT-3 gene modified Schwann cells promote the recovery of transected spinal cord injury." in: Spinal cord, Vol. 45, Issue 1, pp. 15-24, (2007) (PubMed).

Details zu Neurotrophin 3

Target: Neurotrophin 3 (NTF3)

Andere Bezeichnung: NTF3 (NTF3 Produkte)

Synonyme: HDNF antikoerper, NGF-2 antikoerper, NGF2 antikoerper, NT3 antikoerper, NT-3 antikoerper, wu:fl98d04 antikoerper, hdnf antikoerper, ngf-2 antikoerper, ngf2 antikoerper, nt-3 antikoerper, nt3 antikoerper, NTF3 antikoerper, AI316846 antikoerper, AI835689 antikoerper, Nt3 antikoerper, Ntf-3 antikoerper, neurotrophin 3 antikoerper, neurotrophin 3 S homeolog antikoerper, neurotrophin 3 L homeolog antikoerper, NTF3 antikoerper, ntf3 antikoerper, ntf3.S antikoerper, Ntf3 antikoerper, ntf3.L antikoerper

Hintergrund: Neurotrophin-3 is a member of a family of neurotrophic factors, that is closely related to both nerve growth factor and brain derived neurotrophic factor. These proteins are involved in the maintenance of the adult nervous system and affect development of neurons in the embryo when it is expressed in human placenta. NT3 deficient mice generated by gene targeting display severe movement defects of the limbs.

Synonyms: HDNF antibody|MGC129711 antibody|Nerve growth factor 2 antibody|Neurotrophic factor antibody|Neurotrophin 3 precursor antibody|Neurotrophin-3 antibody|Neurotrophin3 antibody|NGF 2 antibody|NGF-2 antibody|NGF2 antibody|NT 3 antibody|NT-3 antibody|NT3 antibody|NTF 3 antibody|NTF3 antibody|NTF3_HUMAN antibody

UniProt: P20783

Pathways: RTK Signalweg, Neurotrophin Signalübertragung