ITGA5 Antikörper (AA 787-992)

Produktnummer ABIN3043256

Produktdetails anti-ITGA5 Antikörper

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Bindungsspezifität: AA 787-992

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITGA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Verwendungszweck: Rabbit IgG polyclonal antibody for Integrin alpha-5(ITGA5) detection. Tested with WB, FCM in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Integrin alpha-5(ITGA5) detection. Tested with WB, FCM in Human,Mouse,Rat.
Gene Name: integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
Protein Name: Integrin alpha-5

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Integrin alpha 5 recombinant protein (Position: E787-E992). Human Integrin alpha 5 shares 86% amino acid (aa) sequence identity with mouse Integrin alpha 5.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for Integrin alpha 5 is approximately 0.25 ng/lane under reducing conditions.
Flow Cytometry: Concentration:1-3 μg/1x106 cells, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-ITGA5 Antikörper (ABIN3043256)

Chen, Sun, Liu, Tong, Meng: "Silencing of Paternally Expressed Gene 10 Inhibits Trophoblast Proliferation and Invasion." in: PLoS ONE, Vol. 10, Issue 12, pp. e0144845, (2015) (PubMed).

Zhang, Ren, Luo, Fan, Liu, Liang, Ma, Yu, Bai: "A small physiological electric field mediated responses of extravillous trophoblasts derived from HTR8/SVneo cells: involvement of activation of focal adhesion kinase signaling." in: PLoS ONE, Vol. 9, Issue 3, pp. e92252, (2014) (PubMed).

Huang, Lian, Chen, Yang, Yang: "Characterization of rat hair follicle stem cells selected by vario magnetic activated cell sorting system." in: Acta histochemica et cytochemica, Vol. 42, Issue 5, pp. 129-36, (2009) (PubMed).

Details zu ITGA5

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Andere Bezeichnung: ITGA5 (ITGA5 Produkte)

Hintergrund: Integrin alpha-5, also known as FNRA or VLA5A, is a protein that in humans is encoded by the ITGA5 gene. The product of this gene belongs to the integrin alpha chain family. Integrins are integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

Synonyms: CD49 antigen-like family member E antibody|CD49e antibody|Fibronectin Receptor alpha antibody|Fibronectin receptor subunit alpha antibody|Fibronectin receptor, alpha subunit antibody|FNRA antibody|Integrin alpha 5 (fibronectin receptor alpha) antibody|Integrin alpha-5 antibody|Integrin alpha-5 light chain antibody|Integrin alpha-F antibody|Integrin, alpha 5 (fibronectin receptor, alpha polypeptide) antibody|ITA5_HUMAN antibody|ITGA 5 antibody|ITGA5 antibody|Very Late Activation Protein 5 alpha antibody|Very late activation protein 5, alpha subunit antibody|VLA-5 antibody|VLA5 antibody|VLA5A antibody

Gen-ID: 3678

UniProt: P08648

Pathways: Integrin Complex