KIF2C Antikörper (AA 531-725)

Produktnummer ABIN3043278

Produktdetails anti-KIF2C Antikörper

Target: KIF2C (Kinesin Family Member 2C (KIF2C))

Bindungsspezifität: AA 531-725

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIF2C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Kinesin-like protein KIF2C(KIF2C) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Kinesin-like protein KIF2C(KIF2C) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: kinesin family member 2C
Protein Name: Kinesin-like protein KIF2C

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human MCAK recombinant protein (Position: G531-Q725). Human MCAK shares 87% amino acid (aa) sequence identity with both mouse and rat MCAK.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, The detection limit for MCAK is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu KIF2C

Target: KIF2C (Kinesin Family Member 2C (KIF2C))

Andere Bezeichnung: KIF2C (KIF2C Produkte)

Synonyme: kif2c antikoerper, MGC89391 antikoerper, KIF2C antikoerper, si:ch211-61f14.1 antikoerper, KNSL6 antikoerper, MCAK antikoerper, 4930402F02Rik antikoerper, ESTM5 antikoerper, Knsl6 antikoerper, X83316 antikoerper, KRP2 antikoerper, kcm1 antikoerper, mcak antikoerper, kinesin family member 2C antikoerper, kinesin family member 2C S homeolog antikoerper, KIF2C antikoerper, kif2c antikoerper, Kif2c antikoerper, kif2c.S antikoerper

Hintergrund: Kinesin-like protein KIF2C is a protein that in humans is encoded by the KIF2C gene. It is mapped to 1p34.1. The protein encoded by this gene is a member of kinesin-like protein family. Most proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein acts to regulate microtubule dynamics in cells and is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation. KIF2C uses microtubule depolymerizing activity to correct improper microtubule attachments at kinetochores.

Synonyms: 4930402F02Rik antibody|ESTM5 antibody|KIF 2C antibody|kif2c antibody|KIF2C_HUMAN antibody|Kinesein Family Member 2C antibody|Kinesin family member 2C antibody|kinesin like 6 (mitotic centromere associated kinesin) antibody|Kinesin like 6 antibody|Kinesin like protein 6 antibody|Kinesin like protein KIF2C antibody|Kinesin-like protein 6 antibody|Kinesin-like protein KIF2C antibody|KNS L6 antibody|KNSL 6 antibody|KNSL6 antibody|MCAK antibody|MGC11883 antibody|Mitotic centromere associated kinesin antibody|Mitotic centromere-associated kinesin antibody|OTTHUMP00000010066 antibody|X83316 antibody

Gen-ID: 11004

UniProt: Q99661

Pathways: Microtubule Dynamics