Lipocalin 2 Antikörper (AA 21-200)

Produktnummer ABIN3043290

Produktdetails anti-Lipocalin 2 Antikörper

Target: Lipocalin 2 (LCN2)

Bindungsspezifität: AA 21-200

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Lipocalin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Neutrophil gelatinase-associated lipocalin(LCN2) detection. Tested with WB, IHC-P, ELISA in Mouse, Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Neutrophil gelatinase-associated lipocalin(LCN2) detection. Tested with WB, IHC-P, ELISA in Mouse, Rat.
Gene Name: lipocalin 2
Protein Name: Neutrophil gelatinase-associated lipocalin

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived mouse Lipocalin 2 recombinant protein (Position: Q21-N200). Mouse Lipocalin 2 shares 62 % and 81.1 % amino acid (aa) sequence identity with human and rat Lipocalin 2, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse

Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-Lipocalin 2 Antikörper (ABIN3043290)

Narayan, Duan, Jiang, Li, Paka, Yamin, Friedman, Weir, Goldberg: "Late intervention with the small molecule BB3 mitigates postischemic kidney injury." in: American journal of physiology. Renal physiology, Vol. 311, Issue 2, pp. F352-61, (2017) (PubMed).

Li, Wang, He, Chen, Yu: "Expression of neutrophil gelatinase-associated lipocalin in low osmolar contrast-induced nephropathy in rats and the effect of N-acetylcysteine." in: Experimental and therapeutic medicine, Vol. 12, Issue 5, pp. 3175-3180, (2016) (PubMed).

Details zu Lipocalin 2

Target: Lipocalin 2 (LCN2)

Andere Bezeichnung: LCN2 (LCN2 Produkte)

Synonyme: LCN2 antikoerper, 24p3 antikoerper, MSFI antikoerper, NGAL antikoerper, AW212229 antikoerper, Sip24 antikoerper, lipocalin 2 antikoerper, LCN2 antikoerper, Lcn2 antikoerper

Hintergrund: Europhile gelatinase-associated lipocalin (NGAL) is a protein that in humans is encoded by the LCN2 gene. The binding of lipocalin-2 to bacterial siderophores is important in the innate immune response to bacterial infection. Upon encountering invading bacteria the toll-like receptors on immune cells stimulate the synthesis and secretion of lipocalin-2. Secreted lipocalin-2 then limits bacterial growth by sequestering iron-containing siderophores. Lipocalin-2 also functions as a growth factor.

Synonyms: 24p3 antibody|25 kDa alpha 2 microglobulin related subunit of MMP9 antibody|25 kDa alpha-2-microglobulin-related subunit of MMP-9 antibody|Alpha 2 microglobulin related protein antibody|HGNC:6526 antibody|HNL antibody|Lcn 2 antibody|Lcn2 antibody|Lipocalin-2 antibody|Migration stimulating factor inhibitor antibody|MSFI antibody|Neutrophil gelatinase associated lipocalin antibody|Neutrophil gelatinase associated lipocalin precursor antibody|Neutrophil gelatinase-associated lipocalin antibody|NGAL antibody|NGAL_HUMAN antibody|Oncogene 24p3 antibody|Oncogenic lipocalin 24p3 antibody|P25 antibody|Siderocalin antibody|siderocalin LCN2 antibody|SV40 induced 24P3 protein antibody|Uterocalin antibody

Gen-ID: 16819

UniProt: P11672

Pathways: Cellular Response to Molecule of Bacterial Origin, Transition Metal Ion Homeostasis