Dystrophin Antikörper (AA 3076-3404)

Produktnummer ABIN3043317

Produktdetails anti-Dystrophin Antikörper

Target: Dystrophin (DMD)

Bindungsspezifität: AA 3076-3404

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dystrophin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Dystrophin(DMD) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Dystrophin(DMD) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: dystrophin
Protein Name: Dystrophin

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Dystrophin recombinant protein (Position: H3076-D3404). Human Dystrophin shares 100% amino acid (aa) sequence identity with mouse Dystrophin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human,Mouse, Rat , The detection limit for Dystrophin is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu Dystrophin

Target: Dystrophin (DMD)

Andere Bezeichnung: DMD (DMD Produkte)

Synonyme: DMD antikoerper, Dmd antikoerper, MGC83347 antikoerper, DKFZp459C1629 antikoerper, dmd antikoerper, MGC79631 antikoerper, DKFZp468A1620 antikoerper, Dp71 antikoerper, cb664 antikoerper, zfDYS antikoerper, im:6911785 antikoerper, zgc:110165 antikoerper, BMD antikoerper, CMD3B antikoerper, DXS142 antikoerper, DXS164 antikoerper, DXS206 antikoerper, DXS230 antikoerper, DXS239 antikoerper, DXS268 antikoerper, DXS269 antikoerper, DXS270 antikoerper, DXS272 antikoerper, DXSmh7 antikoerper, DXSmh9 antikoerper, Dp427 antikoerper, dys antikoerper, mdx antikoerper, pke antikoerper, DNADMD1 antikoerper, RATDMD antikoerper, CG17750 antikoerper, CG31175 antikoerper, CG34157 antikoerper, CG7240 antikoerper, CG7243 antikoerper, CG7344 antikoerper, DLP antikoerper, DLP1 antikoerper, DLP186 antikoerper, DLP2 antikoerper, DLP3 antikoerper, DmDLP antikoerper, DmDYS antikoerper, Dmel\\CG34157 antikoerper, Dp117 antikoerper, Dp186 antikoerper, Dp205 antikoerper, GI3046716 antikoerper, IDLP antikoerper, det antikoerper, dmDLP antikoerper, dmDp186 antikoerper, dmDys antikoerper, dystrophin antikoerper, dystrophin, gene 1 L homeolog antikoerper, dystrophin, gene 1 antikoerper, dystrophin, muscular dystrophy antikoerper, Dystrophin antikoerper, DMD antikoerper, LOC708073 antikoerper, dmd.1.L antikoerper, LOC465557 antikoerper, dmd.1 antikoerper, dmd antikoerper, Dmd antikoerper, Dys antikoerper

Hintergrund: Dystrophin, also known as DMD, is a rod-shaped cytoplasmic protein, and a vital part of a protein complex that connects the cytoskeleton of a muscle fiber to the surrounding extracellular matrix through the cell membrane. It is mapped to Xp21.2-p21.1. This complex is variously known as the costamere or thedystrophin-associated protein complex. Many muscle proteins, such as α-dystrobrevin, syncoilin, synemin, sarcoglycan, dystroglycan, and sarcospan, colocalize with dystrophin at the costamere. Dystrophin is a protein located between the sarcolemma and the outermost layer of myofilaments in the muscle fiber (myofiber). It is a cohesive protein, linking actin filaments to another support protein that resides on the inside surface of each muscle fiber's plasma membrane (sarcolemma).

Synonyms: Apo dystrophin antibody|BMD antibody|CMD3B antibody|DMD antibody|DMD_HUMAN antibody|Duchenne muscular dystrophy protein antibody|DXS142 antibody|DXS164 antibody|DXS206 antibody|DXS230 antibody|DXS239 antibody|DXS268 antibody|DXS269 antibody|DXS270 antibody|DXS272 antibody|Dystrophin antibody|Muscular dystrophy Duchenne and Becker types antibody

Gen-ID: 1756

UniProt: P11532

Pathways: Skeletal Muscle Fiber Development